N-methyl-N-phenyl-8-hydroxy-1-naphthamide

Base Information

• Chemical Name: N-methyl-N-phenyl-8-hydroxy-1-naphthamide
• CAS No.: 111054-66-1
• Molecular Formula: C₁₈H₁₅NO₂
• Molecular Weight: 277.323
• Mol file: 111054-66-1.mol

Synonyms:N-methyl-N-phenyl-8-hydroxy-1-naphthamide

Chemical Property of N-methyl-N-phenyl-8-hydroxy-1-naphthamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-N-phenyl-8-hydroxy-1-naphthamide

There total 2 articles about N-methyl-N-phenyl-8-hydroxy-1-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-N-methyl-N-phenylaminonaphtho<1,8-bc>furylium perchlorate → N-methyl-N-phenyl-8-hydroxy-1-naphthamide (111054-66-1)

Guidance literature:

With water; In N,N-dimethyl-formamide; at 15 - 20 ℃; for 0.166667h;

Reference yield: 88.0%

1,8-naphtholactone (5247-85-8) + N-methylaniline (100-61-8) → N-methyl-N-phenyl-8-hydroxy-1-naphthamide (111054-66-1)

Guidance literature:

In toluene; for 0.1h; Heating;

Reference yield:

N-methyl-N-phenyl-8-hydroxy-1-naphthamide (111054-66-1) → 1,8-naphtholactone (5247-85-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) POCl₃, 2) aq.HClO₄ / 1) reflux, 5-7 min, 2) 0 deg C, 20-30 min

2: 100 percent / H₂O / dimethylformamide / 0.08 h / Heating

With perchloric acid; water; trichlorophosphate; In N,N-dimethyl-formamide;

upstream raw materials:

1,8-naphtholactone

N-methylaniline

Downstream raw materials:

1,8-naphtholactone

8-hydroxy-1-naphthonitrile

Refernces