Technology Process of (10S)-10-[(2R)-(acetyloxy)(phenyl)ethanoate]-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
There total 4 articles about (10S)-10-[(2R)-(acetyloxy)(phenyl)ethanoate]-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium formate; palladium 10% on activated carbon / dichloromethane; methanol; water / 1 h / 20 °C / Inert atmosphere
2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 1 h / Reflux
With
dmap; palladium 10% on activated carbon; ammonium formate; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane; water;
- Guidance literature:
-
With
dicyclohexyl-carbodiimide;
dmap;
In
dichloromethane;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium permanganate on alumina; sodium carbonate; peroxyacetic acid; acetic acid / dichloromethane / 1.67 h / Reflux
2: ammonium formate; palladium 10% on activated carbon / dichloromethane; methanol; water / 1 h / 20 °C / Inert atmosphere
3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 1 h / Reflux
With
dmap; peroxyacetic acid; palladium 10% on activated carbon; potassium permanganate on alumina; ammonium formate; sodium carbonate; acetic acid; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane; water;