O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride

Base Information

• Chemical Name: O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride
• CAS No.: 51514-08-0
• Molecular Formula: C₁₉H₁₈ClNO₅
• Molecular Weight: 375.809
• Mol file: 51514-08-0.mol

Synonyms:O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride

Chemical Property of O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride

There total 1 articles about O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-acetyl-N-benzyloxycarbonyl L-tyrosine (51514-13-7) → O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride (51514-08-0)

Guidance literature:

With diethyl ether; phosphorus pentachloride;

DOI:10.1002/hlca.19480310215 DOI:10.1021/ja01234a034

Reference yield:

O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride (51514-08-0) → (S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-(4-hydroxy-phenyl)-propionic acid (1050-28-8)

Guidance literature:

Multi-step reaction with 3 steps

1: ethyl acetate

2: aq. NaOH solution

3: palladium; acetic acid; methanol / Hydrogenation

With methanol; sodium hydroxide; palladium; acetic acid; ethyl acetate;

Reference yield:

O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride (51514-08-0) → N-{N-[N-(O-acetyl-N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosyl]-L-tyrosyl}-L-tyrosine ethyl ester

Guidance literature:

With 1,4-dioxane; ethyl acetate;

DOI:10.1021/ja01234a034

upstream raw materials:

O-acetyl-N-benzyloxycarbonyl L-tyrosine

Downstream raw materials:

N-(O-acetyl-N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester

N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine

Z-L-Tyr-Gly-OMe

(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-(4-hydroxy-phenyl)-propionic acid