1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate)

Base Information

• Chemical Name: 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate)
• CAS No.: 87611-40-3
• Molecular Formula: C₁₉H₂₆N₂O₄
• Molecular Weight: 346.426
• Mol file: 87611-40-3.mol

Synonyms:1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate)

Chemical Property of 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate)

There total 2 articles about 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-4-cyanocyclohexane-1-ylcarboxylic acid (15177-68-1) + 4-Cyano-cyclohexanecarboxylic acid 1-chloro-propyl ester → 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate) (87611-40-3)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; Multistep reaction; 2.) trichloroethylene, reflux, 8 h;

DOI:10.1021/jm00154a004

Reference yield:

→ 1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate) (87611-40-3)

Guidance literature:

Reference yield:

1,1-propandiol bis-(trans-4-cyanocyclohexanecarboxylate) (87611-40-3) → 1,1-Propandiol bis-(trans-4-aminomethylcyclohexanecarboxylate) dihydrochloride (87589-43-3)

Guidance literature:

With chloroform; hydrogen; platinum(IV) oxide; In ethanol; at 22 ℃; for 15h; under 25502 Torr; Yield given;

DOI:10.1021/jm00154a004

upstream raw materials:

trans-4-cyanocyclohexane-1-ylcarboxylic acid

Downstream raw materials:

1,1-Propandiol bis-(trans-4-aminomethylcyclohexanecarboxylate) dihydrochloride

Refernces

• 1、 -. "Antifibrinolytically active derivatives of tranexamic acid". . . Retrieved 2008/06/13.