(R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride

Base Information Edit

Chemical Name:(R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride
CAS No.:120570-09-4
Molecular Formula:C₁₅H₂₂N₂*2ClH
Molecular Weight:303.275
Hs Code.:
European Community (EC) Number:624-771-3
Mol file:120570-09-4.mol

Synonyms:120570-09-4;(R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride;(R)-N-((S)-1-phenylethyl)quinuclidin-3-aMine (dihydrochloride);(3R)-N-[(1S)-1-phenylethyl]-1-azabicyclo[2.2.2]octan-3-amine;dihydrochloride;(3R)-N-[(1S)-1-PHENYLETHYL]-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE DIHYDROCHLORIDE;[S-(R,S)]-(+)-N-(1-PHENYLETHYL)-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE,DIHYDROCHLORIDE;[S-(R,S)]-(+)-N-(1-Phenylethyl)-1-Azabicyclo[2.2.2]Octan-3-Amine Dihydrochloride;SCHEMBL9486745;1-Azabicyclo[2.2.2]octan-3-amine, N-[(1R)-1-phenylethyl]-, hydrochloride (1:2), (3S)-;CS-M0936;VEA57009;AKOS022180219;CS-13394;J-004361;(S-(R* S*))-(+)-N-(1-PHENYLETHYL)-1- AZ&;(R)-N-((S)-1-Phenylethyl)quinuclidin-3-aminedihydrochloride;(+)-N-(1(S)-Phenylethyl)-1-azabicyclo[2.2.2]octan-3(R)-amine dihydrochloride,98%;(+)-N-(1(S)-Phenylethyl)-1-azabicyclo[2.2.2]octan-3(R)-amine hydrochloride, 98%;[S-(R,S)]-(+)-N-(1-PHENYLETHYL)-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE,2HCL

Suppliers and Price of (R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amineDihydrochloride
100mg
$ 565.00

American Custom Chemicals Corporation
[S-(R,S)]-(+)-N-(1-PHENYLETHYL)-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE DIHYDROCHLORIDE 95.00%
10G
$ 2428.53

American Custom Chemicals Corporation
[S-(R,S)]-(+)-N-(1-PHENYLETHYL)-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE DIHYDROCHLORIDE 95.00%
5G
$ 911.99

American Custom Chemicals Corporation
[S-(R,S)]-(+)-N-(1-PHENYLETHYL)-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE DIHYDROCHLORIDE 95.00%
1G
$ 621.69

Total 7 raw suppliers

Chemical Property of (R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride Edit

Chemical Property:

Melting Point:285 °C (dec.)(lit.)
Refractive Index: ">
Boiling Point:394.4°Cat760mmHg
Flash Point:192.3°C
PSA：15.27000
Density:g/cm³
LogP:4.36420
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:302.1316542
Heavy Atom Count:19
Complexity:239

Purity/Quality:

98%min ^*data from raw suppliers

(3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amineDihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC2CN3CCC2CC3.Cl.Cl
Isomeric SMILES:C[C@@H](C1=CC=CC=C1)N[C@H]2CN3CCC2CC3.Cl.Cl
Uses (3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amine Dihydrochloride is the derivative of 3-Quinuclidinone Hydrochloride (Q795795), which is used in the synthesis of cevimeline, a thiolating agent. Also used in the preparation of novel CB1 and CB2 cannabinoid receptor ligands.

Technology Process of (R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride

There total 9 articles about (R)-N-((S)-1-Phenylethyl)quinuclidin-3-amine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%