Cyclopentanamine, 2-(2-propenyl)- (9CI)

Base Information

• Chemical Name: Cyclopentanamine, 2-(2-propenyl)- (9CI)
• CAS No.: 120871-54-7
• Molecular Formula: C8H15 N
• Molecular Weight: 125.2114
• Mol file: 120871-54-7.mol

Synonyms:Cyclopentanamine,2-(2-propenyl)- (9CI); 1-Allyl-2-aminocyclopentane

Chemical Property of Cyclopentanamine, 2-(2-propenyl)- (9CI)

Chemical Property:

• PSA: 26.02000
• LogP: 2.39020

Purity/Quality:

2-(Prop-2-en-1-yl)cyclopentan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopentanamine, 2-(2-propenyl)- (9CI)

There total 5 articles about Cyclopentanamine, 2-(2-propenyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

(E)-2-allylcyclopentanone oxime (64897-66-1) → (1R,2S)-2-Allyl-cyclopentylamine (81097-02-1,120871-54-7,124574-03-4,134786-11-1,134786-41-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; room temperature-45 deg C;

Reference yield:

Cyclopentanone oxime (1192-28-5) → (1R,2S)-2-Allyl-cyclopentylamine (81097-02-1,120871-54-7,124574-03-4,134786-11-1,134786-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1: BuLi / -30 deg C -> room temperature

2: 11 percent / LiAlH₄ / tetrahydrofuran / room temperature-45 deg C

With lithium aluminium tetrahydride; n-butyllithium; In tetrahydrofuran;

Reference yield:

cyclopentanone (120-92-3) → (1R,2S)-2-Allyl-cyclopentylamine (81097-02-1,120871-54-7,124574-03-4,134786-11-1,134786-41-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NH₂NH₂*HCl / pyridine; ethanol / Heating

2: BuLi / -30 deg C -> room temperature

3: 11 percent / LiAlH₄ / tetrahydrofuran / room temperature-45 deg C

With lithium aluminium tetrahydride; n-butyllithium; hydrazine hydrochloride; In tetrahydrofuran; pyridine; ethanol;

upstream raw materials:

(E)-2-allylcyclopentanone oxime

Cyclopentanone oxime

cyclopentanone

Downstream raw materials:

acide cis-N-tosyl perhydrocyclopentapyrrole-2-carboxylique

acide (2RS,3aSR,6aRS)-N-tosyl perhydrocyclopentapyrrole-2-carboxylique

acide cis-N-tosyl perhydrocyclopentapyrrole-2-carboxylique

(2RS,3aSR,6aRS)-N-tosyl perhydrocyclopentapyrrole-2-methanol

Refernces

• 1、 Kawada, Kenji,Tsushima, Tadahiko. "SYNTHESIS OF MONOCYCLIC ANALOGUES OF A POTENT THROMBOXANE RECEPTOR ANTAGONIST, (+/-)-(5Z)-7-BICYCLOHEPT-2-EXO-YL>HEPTENOIC ACID (S-145)". . p. 573 - 578. Retrieved 2007/10/02.