tert-Butyl (4-chloropyridin-2-yl)carbamate

Base Information Edit

Chemical Name:tert-Butyl (4-chloropyridin-2-yl)carbamate
CAS No.:130721-78-7
Molecular Formula:C10H13ClN2O2
Molecular Weight:228.678
Hs Code.:2933399090
European Community (EC) Number:889-284-2
DSSTox Substance ID:DTXSID40363969
Wikidata:Q72502710
Mol file:130721-78-7.mol

Synonyms:130721-78-7;tert-Butyl (4-chloropyridin-2-yl)carbamate;(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester;2-Boc-amino-4-chloropyridine;tert-Butyl 4-Chloropyridin-2-ylcarbamate;Tert-butyl N-(4-chloropyridin-2-yl)carbamate;2-(Boc-amino)-4-chloropyridine;MFCD05663519;tert-butyl(4-chloropyridin-2-yl)carbamate;Carbamic acid, (4-chloro-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, N-(4-chloro-2-pyridinyl)-, 1,1-dimethylethyl ester;tert-butyl N-(4-chloro-2-pyridyl)carbamate;SCHEMBL437390;DTXSID40363969;BCP26310;CL0027;AKOS015838124;AB21843;CS-W010399;AC-23287;AM803150;AS-11133;SY106600;FT-0656863;EN300-1585488;tert-butyl N-(4-chloranylpyridin-2-yl)carbamate;(4-Chloropyridin-2-yl)carbamicacidtert-butylester;A806136;J-524695;(4-Chloro-pyridin-2-yl)-carbamic acidtert-butyl ester;(4-Chloropyridin-2-yl)-carbamic acid tert-butyl ester;(4-Chloropyridin-2-yl)carbamic acid tert-butyl ester;N-(4-chloro-2-pyridinyl)carbamic acid tert-butyl ester;(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester, AldrichCPR;Carbamic acid,N-(4-chloro-2-pyridinyl)-,1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl (4-chloropyridin-2-yl)carbamate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester
5g
$ 305.00

TRC
(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester
1g
$ 95.00

Sigma-Aldrich
(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester Aldrich
1g
$ 637.00

Matrix Scientific
(4-Chloro-pyridin-2-yl)-carbamic acidtert-butyl ester
25g
$ 355.00

Matrix Scientific
(4-Chloro-pyridin-2-yl)-carbamic acidtert-butyl ester
1g
$ 34.00

Matrix Scientific
(4-Chloro-pyridin-2-yl)-carbamic acidtert-butyl ester
5g
$ 114.00

Crysdot
tert-Butyl(4-chloropyridin-2-yl)carbamate 98%
5g
$ 114.00

Crysdot
tert-Butyl(4-chloropyridin-2-yl)carbamate 98%
1g
$ 35.00

Chemcia Scientific
(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester ＞97%
25 G
$ 330.00

Atlantic Research Chemicals
tert-Butyl4-Chloropyridin-2-ylcarbamate 95%
1gm:
$ 236.82

Total 57 raw suppliers

Chemical Property of tert-Butyl (4-chloropyridin-2-yl)carbamate Edit

Chemical Property:

Appearance/Colour:White to off-white powder
Vapor Pressure:0.00545mmHg at 25°C
Melting Point:(dec)
Refractive Index:1.557
Boiling Point:274.3 °C at 760 mmHg
PKA:11.89±0.70(Predicted)
Flash Point:119.7 °C
PSA：51.22000
Density:1.245 g/cm³
LogP:3.15500
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:228.0665554
Heavy Atom Count:15
Complexity:228

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-Chloro-pyridin-2-yl)-carbamic acid tert-butyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22-43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC=CC(=C1)Cl

Technology Process of tert-Butyl (4-chloropyridin-2-yl)carbamate

There total 7 articles about tert-Butyl (4-chloropyridin-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 19798-80-2
2-Amino-4-chloropyridine

: 24424-99-5
di-tert-butyl dicarbonate

: 130721-78-7
tert-butyl (4-chloropyridin-2-yl) carbamate

Guidance literature:: 2-Amino-4-chloropyridine; With sodium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 0.166667h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1002/anie.201501374