tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate

Base Information

• Chemical Name: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate
• CAS No.: 139115-91-6
• Molecular Formula: C9H19NO4
• Molecular Weight: 205.254
• Hs Code.: 2924199090
• European Community (EC) Number: 695-517-7
• DSSTox Substance ID: DTXSID00410988
• Nikkaji Number: J1.670.524A
• Wikidata: Q82217397
• Mol file: 139115-91-6.mol

Synonyms:139115-91-6;tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate;2-(2-Boc-aminoethoxy)ethanol;N-Boc-PEG2-alcohol;Boc-NH-PEG2;Tert-butyl N-[2-(2-hydroxyethoxy)ethyl]carbamate;t-boc-N-amido-PEG2-alcohol;MFCD04038542;PROTAC Linker 11;BocNH-PEG2-OH;Boc-NH-PEG2-OH;tert-butyl 2-(2-hydroxyethoxy)ethylcarbamate;2-[2-(Boc-amino)-ethoxy]-ethanol;N-Boc-2-(2-hydroxyethoxy)ethylamine;2-(2-tert-Butoxycarbonylaminoethoxy)ethanol;tert-butyl [2-(2-hydroxyethoxy)ethyl]carbamate;2-[2-[(tert-Butoxycarbonyl)amino]ethoxy]ethanol;N-[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester;Carbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester;tert-Butyl(2-(2-hydroxyethoxy)ethyl)carbamate;tert-butyl[2-(2-hydroxyethoxy)ethyl]carbamate;2-[2-(Boc-amino)ethoxy]ethanol;2-[2-(tert-Butoxycarbonylamino)ethoxy]ethanol;SCHEMBL674127;AMY4444;DTXSID00410988;KSFVNEXYCULLEJ-UHFFFAOYSA-N;MFCD09753879;AKOS000799085;CS-W004896;HY-W004896;N-Boc-2-(2-hydroxyethoxy)-ethylamine;5-t-butyloxycarbonylamino-3-oxapentanol;t-Boc-N-amido-PEG-OH, MW 1,000;t-Boc-N-amido-PEG-OH, MW 2,000;t-Boc-N-amido-PEG-OH, MW 3,400;t-Boc-N-amido-PEG-OH, MW 5,000;2-[2-(Boc-amino)ethoxy]ethanol, 97%;AS-17913;BP-23275;BP-25994;BP-25995;BP-25996;BP-25997;BP-25998;SY059537;SY223912;t-Boc-N-amido-PEG-OH, MW 10,000;2-[2-(t-butoxycarbonylamino)ethoxy]ethanol;B5745;tert-butyl-2-(2-hydroxyethoxy)ethylcarbamate;EN300-119687;S10534;tert-butyl[2-(2--hydroxyethoxy)ethyl]carbamate;2-(2-(tert-butyloxycarbonylamino)ethoxy)ethanol;2-(N-tert-butoxycarbonyl-2-aminoethoxy)-ethanol;tert-Butyl (2-(2-hydroxyethoxyl)ethyl)carbamate;T-BUTYL 2-(2-HYDROXYETHOXY)ETHYLCARBAMATE;[2-(2-Hydroxyethoxy)ethyl]-carbamic Acid Tert-Butyl Ester;[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester;[2-(2-Hydroxy-ethoxy)-ethyl]-carbamic acid tert-butyl ester;Carbamic acid, [2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester

Chemical Property of tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate

Chemical Property:

• Vapor Pressure: 1.01E-05mmHg at 25°C
• Refractive Index: 1.454
• Boiling Point: 332.9°Cat760mmHg
• PKA: 12.20±0.46(Predicted)
• Flash Point: 155.1°C
• PSA: 67.79000
• Density: 1.061g/cm³
• LogP: 0.91090
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 205.13140809
• Heavy Atom Count: 14
• Complexity: 165

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-Boc-aminoethoxy)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25-36-37-38
• Safety Statements: 36/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NCCOCCO
• Description: N-Boc-PEG2-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
• Uses: 2-[2-(Boc-amino)ethoxy]ethanol is N-terminal protected 2-(2-aminoethoxy)ethanol. It is generally used as a molecular spacer/linker. Some of such applications are:Synthesis of biotinylated HaloLigands to prepare quantum dot adducts for HaloTag protein-mediated specific labeling of live cells.It is one of the key precursors for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagent used for identification of tyroscherin binding proteins.It can be used to link HaloTag enzyme with fluorescent zinc indicator, ZIMIR to monitor the dynamics of regulated secretion of zinc in real time.It can also be used to synthesize amphiphiles for DNA and siRNA delivery.