Methyl candesartan

Base Information Edit

Chemical Name:Methyl candesartan
CAS No.:139481-69-9
Molecular Formula:C25H22N6O3
Molecular Weight:454.488
Hs Code.:
European Community (EC) Number:604-139-3
UNII:NG25Z8EW4V
ChEMBL ID:CHEMBL308884
DSSTox Substance ID:DTXSID60161060
Nikkaji Number:J557.852C
Wikidata:Q27284852
Mol file:139481-69-9.mol

Synonyms:139481-69-9;Methyl candesartan;Candesartan Methyl Ester;Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate;Candesartan-d5MethylEster;NG25Z8EW4V;CHEMBL308884;Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate;Ethyl-2-ethoxy-1-[[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole]-7-carboxylate;Methyl 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxybenzimidazole-7-carboxylate;Methyl 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-benzimidazole-7-carboxylate;Methyl 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)benzimidazole-7-carboxylate;Methyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate;methyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate;(+/-)-Methyl 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)benzimidazole-7-carboxylate;1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, methyl ester;1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, methyl ester;Methyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (Candesartan Methyl Ester);UNII-NG25Z8EW4V;Candesartan cilexetil impurity I [EP];SCHEMBL1653406;DTXSID60161060;RBPFEPGTRLLUKI-UHFFFAOYSA-N;BCP12918;BDBM50044396;MFCD09263633;MFCD18379253;AKOS015900107;AKOS016001589;DS-12084;SY269620;CS-0151434;NS00024508;D82209;A886000;CANDESARTAN CILEXETIL IMPURITY I [EP IMPURITY];Q27284852;Methyl 2-ethoxy-1-[[2'-(1 H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate;methyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylate;methyl 2-ethoxy-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methylbenzimidazole-7carboxylate;2-Ethoxy-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid methyl ester;Methyl 1-[[2 inverted exclamation mark -(5-Tetrazolyl)-4-biphenylyl]methyl]-2-ethoxybenzimidazole-7-carboxylate;Methyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

Suppliers and Price of Methyl candesartan

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95+%
250mg
$ 742.00

Matrix Scientific
Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95+%
1g
$ 1647.00

Crysdot
Methyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95+%
100g
$ 574.00

Chemenu
Methyl1-((2''-(2H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95%
100g
$ 542.00

Chemenu
Methyl1-((2''-(2H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95%
10g
$ 102.00

Chemenu
Methyl1-((2''-(2H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95%
25g
$ 194.00

Biosynth Carbosynth
Candesartan methyl ester
5 mg
$ 150.00

Biosynth Carbosynth
Candesartan methyl ester
100 mg
$ 1638.00

Biosynth Carbosynth
Candesartan methyl ester
50 mg
$ 901.00

Biosynth Carbosynth
Candesartan methyl ester
25 mg
$ 496.00

Total 69 raw suppliers

Chemical Property of Methyl candesartan Edit

Chemical Property:

Melting Point:169-173°C
Boiling Point:704.488 °C at 760 mmHg
PKA:4.15±0.10(Predicted)
Flash Point:379.861 °C
PSA：107.81000
Density:1.357 g/cm³
LogP:4.50710
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:454.17533859
Heavy Atom Count:34
Complexity:675

Purity/Quality:

99% ^*data from raw suppliers

Methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)-methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC
Uses Candesartan Methyl Ester (Candesartan Cilexetil EP Impurity I) is an intermediate in the preparation of Candesartan (C175575). An intermediate in the preparation of Candesartan (C175575).

Technology Process of Methyl candesartan

There total 15 articles about Methyl candesartan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%