N-[(2,4-dimethylphenyl)methylidene]hydroxylamine

Base Information

• Chemical Name: N-[(2,4-dimethylphenyl)methylidene]hydroxylamine
• CAS No.: 141304-07-6
• Molecular Formula: C9H11 N O
• Molecular Weight: 149.192
• DSSTox Substance ID: DTXSID80400600
• Mol file: 141304-07-6.mol

Synonyms:N-[(2,4-dimethylphenyl)methylidene]hydroxylamine;141304-07-6;Benzaldehyde,2,4-dimethyl-, oxime;Benzaldehyde, 2,4-dimethyl-, oxime (9CI);2,4-dimethylbenzaldehyde oxime;2,4-dimethylbenzaldoxime;DTXSID80400600;ZXOXSHIAPHLSAV-UHFFFAOYSA-N;AKOS017263852

Chemical Property of N-[(2,4-dimethylphenyl)methylidene]hydroxylamine

Chemical Property:

• PSA: 32.59000
• LogP: 2.11150
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 149.084063974
• Heavy Atom Count: 11
• Complexity: 145

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-Dimethylbenzaldehydeoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C=NO)C

Technology Process of N-[(2,4-dimethylphenyl)methylidene]hydroxylamine

There total 10 articles about N-[(2,4-dimethylphenyl)methylidene]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

2,4-dimethylbenzotrichloride (123413-30-9) → 2,4-dimethylbenzonitrile (21789-36-6) + 2,4-dimethylbenzaldehyde oxime (141304-07-6)

Guidance literature:

With hydroxylamine hydrochloride; In pyridine; for 0.333333h; Heating;

DOI:10.1007/BF00699000

Reference yield:

2,4-dimethylbenzaldehyde (15764-16-6) → 2,4-dimethylbenzaldehyde oxime (141304-07-6)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In methanol; at 20 ℃;

Reference yield:

2,4-dimethylbenzaldehyde (15764-16-6) → 2,4-dimethyl-benzaldehyde-(Z)-oxime (141304-07-6)

Guidance literature:

With ethanol;

upstream raw materials:

2,4-dimethylbenzotrichloride

2,4-dimethylbenzaldehyde

2,4-dimethylbenzyl alcohol

para-xylene

Downstream raw materials:

2,4-dimethyl-benzaldehyde (E)-O-(1,1-dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-oxime

C₉H₁₁NO₂

2,4-Xylidine

2,4-dimethylbenzonitrile

Refernces

• 1、 Radhika,Saisree,Harinadha, Babu V.. "Design, docking and synthesis of novel bromo isatin incorporated isoxazole derivatives as vegfr-2 inhibitors". . p. 1 - 7. Retrieved 2019/05/17.
• 2、 -. "ISOXAZOLE DERIVATIVES AS MODULATORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1". Page/Page column 19. . Retrieved 2009/08/16.