5-CFDA N-succinimidyl ester

Base Information

• Chemical Name: 5-CFDA N-succinimidyl ester
• CAS No.: 150206-05-6
• Molecular Formula: C29H19 N O11
• Molecular Weight: 557.46
• DSSTox Substance ID: DTXSID40399369
• Nikkaji Number: J1.075.258B
• Wikidata: Q82201870
• Mol file: 150206-05-6.mol

Synonyms:5-(6)-carboxyfluorescein diacetate succinimidyl ester;5-carboxyfluorescein diacetate succinimidyl ester and 6-carboxyfluorescein diacetate succinimidyl ester;carboxyfluorescein diacetate succinimidyl ester;CFDA-SE;CFDASE;CFSE

Chemical Property of 5-CFDA N-succinimidyl ester

Chemical Property:

• Melting Point: 152-154 °C(lit.)
• Boiling Point: 757.9±70.0 °C(Predicted)
• PSA: 151.81000
• Density: 1.60±0.1 g/cm3(Predicted)
• LogP: 3.26390
• Storage Temp.: 2-8°C
• Solubility.: DMSO: soluble
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 7
• Exact Mass: 557.09581042
• Heavy Atom Count: 41
• Complexity: 1100

Purity/Quality:

98% ^*data from raw suppliers

5-Carboxy-fluorescein diacetate N-succinimidyl ester ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 45-46-23/24/25-36/37/38
• Safety Statements: 53-22-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)C(=O)ON5C(=O)CCC5=O)C(=O)O3)C6=C(O2)C=C(C=C6)OC(=O)C
• Uses: 5-CFDA N-succinimidyl ester is membrane-permeant and can be loaded into cells via incubation. Once inside the cells, 5-CFDA is hydrolyzed by intracellular esterases to 5-carboxyfluorescein. It has been used for labeling human intervertebral disk cells in vitro for fluorescen 5-Carboxy-fluorescein Diacetate N-Succinimidyl Ester is a fluorescein tracer for cell labeling. It was used as a reactant in the bioorthogonal imaging of Aurora Kinase A in live cells.