Ethyl 2-phenylamino-5-thiazolecarboxylate

Base Information

• Chemical Name: Ethyl 2-phenylamino-5-thiazolecarboxylate
• CAS No.: 591777-89-8
• Molecular Formula: C12H12N2O2S
• Molecular Weight: 248.3
• Hs Code.: 2934100090
• DSSTox Substance ID: DTXSID60446147
• Nikkaji Number: J1.891.957E
• Wikidata: Q82264733
• Mol file: 591777-89-8.mol

Synonyms:ETHYL 2-PHENYLAMINO-5-THIAZOLECARBOXYLATE;591777-89-8;Ethyl 2-anilino-1,3-thiazole-5-carboxylate;ethyl 2-(phenylamino)-1,3-thiazole-5-carboxylate;DTXSID60446147;Ethyl2-phenylamino-5-thiazolecarboxylate;Ethyl 2-phenylamino-5-thiazole carboxylate;ethyl 2-(phenylamino)thiazole-5-carboxylate;2-Anilinothiazole-5-carboxylic acid ethyl ester;EN300-6507875

Chemical Property of Ethyl 2-phenylamino-5-thiazolecarboxylate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.63
• Boiling Point: 382.609 °C at 760 mmHg
• Flash Point: 185.196 °C
• PSA: 79.46000
• Density: 1.289 g/cm³
• LogP: 3.13640
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 248.06194880
• Heavy Atom Count: 17
• Complexity: 257

Purity/Quality:

98%Min ^*data from raw suppliers

ETHYL-2-PHENYLAMINO-5-THIAZOLE CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=CN=C(S1)NC2=CC=CC=C2

Technology Process of Ethyl 2-phenylamino-5-thiazolecarboxylate

There total 1 articles about Ethyl 2-phenylamino-5-thiazolecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

ethyl 2-bromo-1,3-thiazole-5-carboxylate (41731-83-3) + aniline (62-53-3) → ethyl 2-anilino-1,3-thiazole-5-carboxylate (591777-89-8)

Guidance literature:

In 1,4-dioxane; at 105 ℃; for 8h;

DOI:10.1002/jhet.5570400225

upstream raw materials:

ethyl 2-bromo-1,3-thiazole-5-carboxylate

aniline

Refernces