TRIFLUORO-ACETIC ACID PHENETHYL ESTER

Base Information

• Chemical Name: TRIFLUORO-ACETIC ACID PHENETHYL ESTER
• CAS No.: 55419-66-4
• Molecular Formula: C10H9F3O2
• Molecular Weight: 218.175
• Hs Code.: 2915900090
• Mol file: 55419-66-4.mol

Synonyms:TRIFLUORO-ACETIC ACID PHENETHYL ESTER

Chemical Property of TRIFLUORO-ACETIC ACID PHENETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.0857mmHg at 25°C
• Refractive Index: 1.452
• Boiling Point: 225.6°C at 760 mmHg
• Flash Point: 72.9°C
• PSA: 26.30000
• Density: 1.245g/cm³
• LogP: 2.33460

Purity/Quality:

98% ^*data from raw suppliers

Phenethyl2,2,2-trifluoroacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRIFLUORO-ACETIC ACID PHENETHYL ESTER

There total 6 articles about TRIFLUORO-ACETIC ACID PHENETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-phenylethanol (60-12-8) + trifluoroacetic anhydride (407-25-0) → trifluoroacetic acid 2-phenylethyl ester (55419-66-4)

Guidance literature:

trifluoroacetic anhydride; With molybdenium(VI) dioxodichloride; In dichloromethane; at 20 ℃; for 0.5h;

2-phenylethanol; In dichloromethane; at 20 ℃; for 0.1h;

DOI:10.1021/jo048363v

Reference yield: 98.0%

2-phenylethanol (60-12-8) + trifluoroacetic acid (76-05-1) → trifluoroacetic acid 2-phenylethyl ester (55419-66-4)

Guidance literature:

at 70 ℃; for 2h;

DOI:10.3390/molecules23010208

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + trifluoroacetic acid (76-05-1) → trifluoroacetic acid 2-phenylethyl ester (55419-66-4)

Guidance literature:

In tetrachloromethane;

DOI:10.1021/ja00452a034

upstream raw materials:

styrene

trifluoroacetic acid

2-phenylethyl p-nitrobenzenesulphonate

2-Phenylaethylmenasylat

Downstream raw materials:

phenethyl azide

ethylbenzene

2,2,2-trifluoroethanol

2-phenylethanol

Refernces

• 1、 Modena,G. et al.. "-". . p. 3392 - 3395. Retrieved 1977.
• 2、 Zell, Thomas,Ben-David, Yehoshoa,Milstein, David. "Unprecedented iron-catalyzed ester hydrogenation. Mild, selective, and efficient hydrogenation of trifluoroacetic esters to alcohols catalyzed by an iron pincer complex". supporting information. p. 4685 - 4689. Retrieved 2014/05/20.
• 3、 Chen, Chien-Tien,Chang, I-Hsin,Lin, Jin-Sheng,Liu, Chin-Jing,Chou, Y-Chen,Kuo, Jen-Huang,Li, Chun-Hsin,Barhate,Hon, Sang-Wen,Li, Tai-Wei,Chao, Shi-Deh,Liu, Chia-Cheng,Li, Ying-Chieh. "Catalytic nucleophilic acyl substitution of anhydrides by amphoteric vanadyl triflate". . p. 3729 - 3732. Retrieved 2007/10/03.