4'-Aminoacetophenone hydrochloride

Base Information

• Chemical Name: 4'-Aminoacetophenone hydrochloride
• CAS No.: 41784-08-1
• Molecular Formula: C8H10ClNO
• Molecular Weight: 171.626
• Hs Code.: 2922399090
• Mol file: 41784-08-1.mol

Synonyms:4-AMINOACETOPHENONE HYDROCHLORIDE;4-AminoacetophenoneHCl;4-AMINOACETOPHENONE HYDROCHLORIDE (P-)

Chemical Property of 4'-Aminoacetophenone hydrochloride

Chemical Property:

• Vapor Pressure: 0.00018mmHg at 25°C
• Boiling Point: 324.3 °C at 760 mmHg
• Flash Point: 149.9 °C
• PSA: 43.09000
• LogP: 2.85460
• Water Solubility.: almost transparency

Purity/Quality:

98%,99%, ^*data from raw suppliers

4'-Aminoacetophenone Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 36/37/38-25
• Safety Statements: 26-36-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4'-Aminoacetophenone hydrochloride

There total 1 articles about 4'-Aminoacetophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(4-nitrophenyl)ethanone (100-19-6) → 4-acetylbenzenaminium hydrochloride (41784-08-1)

Guidance literature:

(4-nitrophenyl)ethanone; With hydrogen; C₁₉H₁₂N₄^(2-)*C₂H₆OS*Co⁽²⁺⁾; In ethanol; at 120 ℃; for 15h; under 30003 Torr; Autoclave;

With hydrogenchloride; In diethyl ether; dichloromethane;

DOI:10.1002/ejoc.202100073

Reference yield: 91.0%

4-acetylbenzenaminium hydrochloride (41784-08-1) + formamide (77287-34-4,77287-35-5,60100-09-6) → N-(4-acetylphenyl)formamide (41656-75-1)

Guidance literature:

In toluene; at 120 ℃; for 3h; Green chemistry;

DOI:10.1002/ejoc.202101114

Reference yield: 80.0%

4-acetylbenzenaminium hydrochloride (41784-08-1) + 5-chloro-4-nitrobenzo[c]-[1,2,5]oxadiazole (5714-17-0) → 1-{4-[(4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino]phenyl}ethanone

Guidance literature:

In diethyl ether; ethanol; at 20 ℃;

DOI:10.1134/S1070363218050092

upstream raw materials:

(4-nitrophenyl)ethanone

Downstream raw materials:

4,11-Dimethylene-2,9-diaza-3,10-diphospha-tricyclo[10.2.2.2^5,8]octadeca-1⁽¹⁵⁾,5⁽¹⁸⁾,6,8⁽¹⁷⁾,12⁽¹⁶⁾,13-hexaene 3,10-dioxide

(p-amino-α-hydroxy-α-methylbenzyl)phosphonous acid hydrochloride

(E)-4-(4-acetylanilino)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one

6-Acetyl-4-[(E)-2-(4-dimethylamino-phenyl)-vinyl]-1-ethyl-quinolinium; iodide

Refernces