METHYL-A-L-ACOSAMINE

Base Information

• Chemical Name: METHYL-A-L-ACOSAMINE
• CAS No.: 54623-24-4
• Molecular Formula: C7H16ClNO3
• Molecular Weight: 197.66
• Mol file: 54623-24-4.mol

Synonyms:METHYL-A-L-ACOSAMINE;METHYL-L-ACOSAMINIDE;METHYL-L-ACOSAMINIDE HYDROCHLORIDE;ACOSAMINE METHYL GLYCOSIDE;ACOSAMINE METHYL GLYCOSIDE HYDROCHLORIDE;Methyl-L-Acosaminide, Acosamine Methyl Glycoside;Acosamine hydrochloride methyl glycoside;METHYL-ALPHA-L-ACOSAMINE

Chemical Property of METHYL-A-L-ACOSAMINE

Chemical Property:

• Melting Point: 130-132°C
• PSA: 64.71000
• LogP: 0.95820
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

98.5% ^*data from raw suppliers

Methyl-a-L-acosamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL-A-L-ACOSAMINE

There total 18 articles about METHYL-A-L-ACOSAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 3-amino-2,3,6-trideoxy-2-iodo-α-DL-altropyranoside hydrochloride (89128-75-6,91366-56-2,116429-71-1,116429-73-3) → (+/-)-Ristosamine methyl ether (32385-06-1,51869-34-2,54623-24-4,64938-62-1,72377-60-7,97413-80-4,115388-97-1,131528-45-5)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); In methanol; toluene; at 80 ℃; for 8h;

Reference yield: 65.0%

methyl 3-amino-2,3,6-trideoxy-2-iodo-α-DL-galactopyranoside hydrochloride (89128-75-6,91366-56-2,116429-71-1,116429-73-3) → methyl 3-amino-2,3,6-trideoxy-α-DL-lyxo-hexopyranoside hydrochloride (32385-06-1,51869-34-2,54623-24-4,64938-62-1,72377-60-7,97413-80-4,115388-97-1,131528-45-5)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); In methanol; toluene; for 1h; Ambient temperature;

Reference yield:

2,3,4,6-tetradeoxy-4',5'-dihydro-2-iodo-2'-trichloromethyl(methyl α-DL-altropyranosido)<3,4-d>oxazole (83803-05-8,88824-29-7,97372-43-5,116558-50-0) → (+/-)-Ristosamine methyl ether (32385-06-1,51869-34-2,54623-24-4,64938-62-1,72377-60-7,97413-80-4,115388-97-1,131528-45-5)

Guidance literature:

With sodium hydroxide; tri-n-butyl-tin hydride; Yield given. Multistep reaction;

DOI:10.1039/c39850000352

upstream raw materials:

methanol

C₁₁H₁₉NO₅

C₁₁H₁₉NO₅

sorbic Acid

Refernces

• 1、 Sammes, Peter G.,Thetford, Dean. "SYNTHESIS OF (L)-DAUNOSAMINE AND RELATED AMINO SUGARS". . p. 111 - 124. Retrieved 2007/10/02.