2,5-Dimethylphenylacetyl chloride

Base Information

• Chemical Name: 2,5-Dimethylphenylacetyl chloride
• CAS No.: 55312-97-5
• Molecular Formula: C10H11ClO
• Molecular Weight: 182.65
• Hs Code.: 2916399090
• Mol file: 55312-97-5.mol

Synonyms:Benzeneacetyl chloride, 2,5-dimethyl-;

Chemical Property of 2,5-Dimethylphenylacetyl chloride

Chemical Property:

• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.529
• Boiling Point: 260.272 °C at 760 mmHg
• Flash Point: 113.995 °C
• PSA: 17.07000
• Density: 1.118 g/cm³
• LogP: 2.61130

Purity/Quality:

98% ^*data from raw suppliers

2-(2,5-Dimethylphenyl)acetylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Dimethylphenylacetyl chloride

There total 9 articles about 2,5-Dimethylphenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.1%

4-bromo-m-xylene (553-94-6) + chloroacetyl chloride (79-04-9) → 2-(2,5-dimethylphenyl)acetyl chloride (55312-97-5)

Guidance literature:

4-bromo-m-xylene; chloroacetyl chloride; With hydrogenchloride; ruthenium(IV) oxide; palladium 10% on activated carbon; In dimethyl sulfoxide; at 100 ℃; for 5h;

With sodium sulfite; In water; dimethyl sulfoxide; at 135 ℃; for 8.25h; Temperature;

Reference yield: 97.5%

2-chloro-1,4-dimethyl-benzene (95-72-7) + chloroacetyl chloride (79-04-9) → 2-(2,5-dimethylphenyl)acetyl chloride (55312-97-5)

Guidance literature:

2-chloro-1,4-dimethyl-benzene; chloroacetyl chloride; With hydrogenchloride; ruthenium(IV) oxide; palladium 10% on activated carbon; In dimethyl sulfoxide; at 120 ℃; for 6h;

With sodium sulfite; In water; dimethyl sulfoxide;

Reference yield: 97.1%

2-bromoacetyl chloride (22118-09-8) + 4-bromo-m-xylene (553-94-6) → 2-(2,5-dimethylphenyl)acetyl chloride (55312-97-5)

Guidance literature:

2-bromoacetyl chloride; 4-bromo-m-xylene; With hydrogenchloride; ruthenium(IV) oxide; palladium 10% on activated carbon; In dimethyl sulfoxide; at 100 ℃; for 5h;

With sodium sulfite; In water; dimethyl sulfoxide; at 135 ℃; for 8.25h;

upstream raw materials:

2-(2,5-dimethylphenyl)acetic acid

(2,5-dimethylphenyl)acetonitrile

2,5-dimethylbenzyl chloride

2-bromoacetyl chloride

Downstream raw materials:

(2,5-Dimethyl-phenyl)-acetic acid 6-[2-(2,5-dimethyl-phenyl)-acetoxy]-hexyl ester

(2,5-Dimethyl-phenyl)-acetic acid 7-[2-(2,5-dimethyl-phenyl)-acetoxy]-heptyl ester

(2,5-Dimethyl-phenyl)-acetic acid 8-[2-(2,5-dimethyl-phenyl)-acetoxy]-octyl ester

(2,5-Dimethyl-phenyl)-acetic acid 10-[2-(2,5-dimethyl-phenyl)-acetoxy]-decyl ester

Refernces

• 1、 -. "Synthesis method and application of 1, 3-bis(2, 5-dimethylphenyl)propan-2-one". Paragraph 0007; 0019; 0026. . Retrieved 2019/07/04.
• 2、 -. "Novel preparation method of spirotetramat". Paragraph 0042-0043. . Retrieved 2018/04/21.