1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE

Base Information

• Chemical Name: 1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE
• CAS No.: 57099-04-4
• Molecular Formula: C16H22O6
• Molecular Weight: 310.347
• Mol file: 57099-04-4.mol

Synonyms:1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE

Chemical Property of 1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE

Chemical Property:

• Vapor Pressure: 2.84E-09mmHg at 25°C
• Refractive Index: 1.572
• Boiling Point: 460.4°Cat760mmHg
• Flash Point: 232.3°C
• PSA: 77.38000
• Density: 1.29g/cm³
• LogP: 0.80140

Purity/Quality:

97% ^*data from raw suppliers

1-2-O-Isopropylidene-3-O-benzyl-D-allofuranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE

There total 16 articles about 1,2-O-ISOPROPYLIDENE-3-BENZYLOXY-D-ALLOFURANOSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2:5,6-di-O-isopropylidene-3-O-benzyl-α-D-allofuranose (22331-21-1) → 3-O-benzyl-1,2-O-isopropylidene-α-D-allofuranose (57099-04-4)

Guidance literature:

With acetic acid; In water; at 20 ℃; for 72h;

DOI:10.1016/j.bmcl.2014.04.050

Reference yield: 94.0%

dibenzyl ether (103-50-4) → 3-O-benzyl-1,2-O-isopropylidene-α-D-allofuranose (57099-04-4)

Guidance literature:

In acetic acid;

Reference yield: 94.0%

→ 3-O-benzyl-1,2-O-isopropylidene-α-D-allofuranose (57099-04-4)

Guidance literature:

upstream raw materials:

1,2:5,6-di-O-isopropylidene-3-O-benzyl-α-D-allofuranose

1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose

Diacetone D-glucose

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

(3S)-O-Benzylallitol

1,2-Isopropylidene-3-O-benzyl-6-O-benzoyl-α-D-allofuranose

3-O-benzyl-1,2-O-isopropylidene-6-O-p-toluenesulfonic-α-D-allofuranose

(3aR,5S,6R,6aR)-6-Benzyloxy-2,2-dimethyl-5-((R)-2-oxo-2λ⁴-[1,3,2]dioxathiolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxole

Refernces

• 1、 -. "NOVEL PROCESS FOR MAKING ALLOFURANOSE FROM GLUCOFURANOSE". Page/Page column 39; 49-50. . Retrieved 2019/12/15.
• 2、 Hassan, Abdalla E.A.,Abou-Elkhair, Reham A.I.,Parker, William B.,Allan, Paula W.,Secrist, John A.. "6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases". . p. 9 - 16. Retrieved 2016/01/09.