Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3

Base Information

• Chemical Name: Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3
• CAS No.: 53921-70-3
• Molecular Formula: C15H10O3
• Molecular Weight: 238.243
• Hs Code.: 2932999099
• Mol file: 53921-70-3.mol

Synonyms:Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3

Chemical Property of Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3

Chemical Property:

• PSA: 46.53000
• LogP: 3.41750
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Dibenzo[b,f]oxepine-10-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3

There total 2 articles about Dibenz[b,f]oxepin-10-carboxylic acid 53921-70-3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-phenoxybenzyl cyanide (25562-98-5) + oxalic acid diethyl ester (95-92-1) → dibenzo[b,f]oxepine-10-carboxylic acid (53921-70-3)

Guidance literature:

2-phenoxybenzyl cyanide; oxalic acid diethyl ester; With ethanol; sodium; at 20 ℃; for 18h;

With sulfuric acid; water; In acetic acid; for 5h; Heating / reflux;

Reference yield:

xanthene (92-83-1) + malonic acid (141-82-2) → 9-dicarboxymethylxanthene (101278-43-7) + dibenzo[b,f]oxepine-10-carboxylic acid (53921-70-3)

Guidance literature:

With manganese triacetate; In acetic acid; for 0.0666667h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/jo00039a010

Reference yield: 100.0%

dibenzo[b,f]oxepine-10-carboxylic acid (53921-70-3) → 10,11-dihydro-dibenz[b,f]oxepin-10-carboxylic acid (109342-71-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 45 ℃; for 18h;

upstream raw materials:

xanthene

malonic acid

2-phenoxybenzyl cyanide

oxalic acid diethyl ester

Downstream raw materials:

10,11-dihydro-dibenz[b,f]oxepin-10-carboxylic acid

Refernces

• 1、 Nishino, Hiroshi,Kamachi, Hironori,Baba, Harumi,Kurosawa, Kazu. "Manganese(III)-Mediated Carbon-Carbon Bond Formation in the Reaction of Xanthenes with Active Methylene Compounds". . p. 3551 - 3557. Retrieved 2007/10/02.