2-Amino-5-bromo-4-pyrimidinol

Base Information

• Chemical Name: 2-Amino-5-bromo-4-pyrimidinol
• CAS No.: 61937-71-1
• Molecular Formula: C4H4BrN3O
• Molecular Weight: 189.999
• Hs Code.: 2933599090
• Mol file: 61937-71-1.mol

Synonyms:2-Amino-5-bromopyrimidin-4-ol;2-Amino-5-bromo-4-hydroxypyrimidine;

Chemical Property of 2-Amino-5-bromo-4-pyrimidinol

Chemical Property:

• Vapor Pressure: 2.68E-06mmHg at 25°C
• Melting Point: 284-285 °C
• Refractive Index: 1.765
• Boiling Point: 379.5 °C at 760 mmHg
• PKA: 7.82±0.50(Predicted)
• Flash Point: 183.3 °C
• PSA: 72.03000
• Density: 2.25 g/cm³
• LogP: 1.10810
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-5-bromo-4-pyrimidinol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Amino-5-bromo-4-pyrimidinol

There total 3 articles about 2-Amino-5-bromo-4-pyrimidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

isocytosine (108-53-2,145358-63-0,674-97-5,176772-97-7) → 2-amino-5-bromo-1H-pyrimidin-6-one (61937-71-1)

Guidance literature:

With bromine; In water; at 20 ℃; for 2h;

DOI:10.1055/s-0032-1316791

Reference yield:

isocytosine (108-53-2,145358-63-0,674-97-5,176772-97-7) → 5-Brom-isocytosin (61937-71-1)

Guidance literature:

With bromine; In acetic acid;

Reference yield:

→ 5-Brom-isocytosin (61937-71-1)

Guidance literature:

2-Amino-4-hydroxy-pyrimidin, N-Brom-succinimid, Eg.;

upstream raw materials:

isocytosine

Downstream raw materials:

2-amino-5-[(4-chlorophenyl)thio]-4(3H)-pyrimidone

Refernces

• 1、 -. "Nitrogen-containing heterocyclic compounds, their production and use". . . Retrieved 2008/06/13.