2-(4-CHLORO-PHENYL)-SUCCINIC ACID

Base Information

• Chemical Name: 2-(4-CHLORO-PHENYL)-SUCCINIC ACID
• CAS No.: 58755-91-2
• Molecular Formula: C10H9ClO4
• Molecular Weight: 228.63
• Hs Code.: 2917399090
• Mol file: 58755-91-2.mol

Synonyms:2-(4-CHLORO-PHENYL)-SUCCINIC ACID

Chemical Property of 2-(4-CHLORO-PHENYL)-SUCCINIC ACID

Chemical Property:

• Vapor Pressure: 2.43E-05mmHg at 25°C
• Refractive Index: 1.59
• Boiling Point: 344.9°C at 760 mmHg
• Flash Point: 162.4°C
• PSA: 74.60000
• Density: 1.454g/cm³
• LogP: 1.98290
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

2-(4-Chlorophenyl)succinicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-CHLORO-PHENYL)-SUCCINIC ACID

There total 5 articles about 2-(4-CHLORO-PHENYL)-SUCCINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C18H24ClN3O4 (109971-36-0) → 2-(4-chlorophenyl)succinic acid (58755-91-2)

Guidance literature:

With hydrogenchloride; for 10h; Heating;

DOI:10.1055/s-1986-31770

Reference yield:

→ 2-(4-chlorophenyl)succinic acid (58755-91-2)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01623a064

Reference yield:

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) → 2-(4-chlorophenyl)succinic acid (58755-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / benzene / 20 h / 20 °C

2: 92 percent / conc. hydrochloric acid / 10 h / Heating

With hydrogenchloride; In benzene;

DOI:10.1055/s-1986-31770

upstream raw materials:

potassium cyanide

4-chlorobenzaldehyde

ethyl 2-cyanoacetate

C₁₈H₂₄ClN₃O₄

Downstream raw materials:

N-[{4-(3-trifluoromethylphenyl)-piperazin-1-yl}-methyl]-3-(4-chlorophenyl)-pyrrolidine-2,5-dione

N-[{4-(4-chlorophenyl)-piperazin-1-yl}-methyl]-3-(4-chlorophenyl)-pyrrolidine-2,5-dione

N-[{4-(2-chlorophenyl)-piperazin-1-yl}-methyl]-3-(4-chlorophenyl)-pyrrolidine-2,5-dione

3-(4-Chloro-phenyl)-1-cyclohexyl-pyrrolidine-2,5-dione

Refernces