1-phospho-alpha-D-galacturonic acid

Base Information

• Chemical Name: 1-phospho-alpha-D-galacturonic acid
• CAS No.: 58865-20-6
• Molecular Formula: C6H11O10P
• Molecular Weight: 274.121
• DSSTox Substance ID: DTXSID201212872
• Nikkaji Number: J2.324.903K
• Wikidata: Q27102451
• Metabolomics Workbench ID: 50954
• Mol file: 58865-20-6.mol

Synonyms:1-phospho-alpha-D-galacturonic acid;D-Galacturonate 1-phosphate;1-Phospho-alpha-D-galacturonate;1-O-phosphono-alpha-D-galactopyranuronic acid;Galacturonate 1-phosphate;58865-20-6;SCHEMBL4939212;CHEBI:17543;DTXSID201212872;alpha-d-galacturonic acid 1-phosphate;C04037;Q27102451;alpha-D-Galactopyranuronic acid, 1-(dihydrogen phosphate)

Chemical Property of 1-phospho-alpha-D-galacturonic acid

Chemical Property:

• PSA: 183.79000
• LogP: -3.01210
• Storage Temp.: -20°C
• XLogP3: -3.4
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 274.00898354
• Heavy Atom Count: 17
• Complexity: 338

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1(C(C(OC(C1O)OP(=O)(O)O)C(=O)O)O)O
• Isomeric SMILES: [C@@H]1([C@H]([C@H](O[C@@H]([C@@H]1O)OP(=O)(O)O)C(=O)O)O)O

Technology Process of 1-phospho-alpha-D-galacturonic acid

There total 5 articles about 1-phospho-alpha-D-galacturonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

D-glucuronic acid (6556-12-3,489-91-8,528-16-5,552-12-5,577-46-8,643-33-4,2240-07-5,6294-16-2,10133-02-5,18402-78-3,18968-14-4,21179-08-8,23018-83-9,33599-45-0,33599-46-1,46171-67-9,46171-69-1,46172-26-3,70021-34-0,71031-08-8,104195-06-4,106499-29-0,124817-72-7) → α-D-glucopyranuronic acid 1-phosphate (6920-57-6,7259-41-8,10345-04-7,13168-11-1,46825-92-7,58865-20-6,69127-38-4)

Guidance literature:

With recombinant Arabidopsis thaliana glucuronokinase; molecular weight around 42 kDa; ATP; magnesium chloride; In aq. buffer; at 37 ℃; pH=7; Reagent/catalyst; chemoselective reaction; Catalytic behavior; Enzymatic reaction;

DOI:10.1039/c4cc10306h

Reference yield: 92.0%

D-galacturonic acid (489-91-8,528-16-5,552-12-5,577-46-8,643-33-4,2240-07-5,6294-16-2,10133-02-5,18402-78-3,18968-14-4,21179-08-8,23018-83-9,33599-45-0,33599-46-1,46171-67-9,46171-69-1,46172-26-3,70021-34-0,71031-08-8,104195-06-4,106499-29-0,124817-72-7) → α-D-galactopyranosyluronic acid phosphate (58865-20-6)

Guidance literature:

With recombinant Bifidobacterium infantis galactokinase; ATP; magnesium chloride; In aq. buffer; at 37 ℃; pH=7; Reagent/catalyst; chemoselective reaction; Catalytic behavior; Enzymatic reaction;

DOI:10.1039/c4cc10306h

Reference yield:

→ α-D-glucopyranuronic acid 1-phosphate (6920-57-6,7259-41-8,10345-04-7,13168-11-1,46825-92-7,58865-20-6,69127-38-4)

Guidance literature:

With platinum on activated charcoal; water; oxygen;

DOI:10.1039/jr9520001578

upstream raw materials:

D-glucuronic acid

D-galacturonic acid

Downstream raw materials:

UDP-glucuronic acid

D-glucurono-6,3-lactone

Refernces

• 1、 Li, Lei,Liu, Yonghui,Li, Tiehai,Wang, Wenjun,Yu, Zaikuan,Ma, Cheng,Qu, Jingyao,Zhao, Wei,Chen, Xi,Wang, Peng G.. "Efficient chemoenzymatic synthesis of novel galacto-N-biose derivatives and their sialylated forms". supporting information. p. 10310 - 10313. Retrieved 2015/06/25.
• 2、 Li, Lei,Liu, Yonghui,Wang, Wenjun,Cheng, Jiansong,Zhao, Wei,Wang, Peng. "A highly efficient galactokinase from Bifidobacterium infantis with broad substrate specificity". experimental part. p. 35 - 39. Retrieved 2012/08/08.