Z-1-HEXENYLBORONIC ACID

Base Information

• Chemical Name: Z-1-HEXENYLBORONIC ACID
• CAS No.: 54354-55-1
• Molecular Formula: C6H13BO2
• Molecular Weight: 127.97722
• Hs Code.: 2931900090
• Mol file: 54354-55-1.mol

Synonyms:Z-1-HEXENYLBORONIC ACID

Chemical Property of Z-1-HEXENYLBORONIC ACID

Chemical Property:

• Boiling Point: 227.8±23.0 °C(Predicted)
• PKA: 9.81±0.43(Predicted)
• PSA: 40.46000
• Density: 0.926±0.06 g/cm3(Predicted)
• LogP: 0.74480

Purity/Quality:

99% ^*data from raw suppliers

Z-1-HEXENYLBORONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-1-HEXENYLBORONIC ACID

There total 6 articles about Z-1-HEXENYLBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

hex-1-yne (693-02-7) + benzo[1,3,2]dioxaborole (274-07-7) → (Z)-1-Hexen-1-boronsaeure (54354-55-1)

Guidance literature:

With water; byproducts: H2, catechol; equiv. amt. of catecholborane added to alkyne under N2, heated to 70°C for 3 h, large excess of water added, stirred overnight; filtered, washed with copious amts. of water;

Reference yield:

(Z)-2-(hex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (91083-23-7) → (Z)-1-Hexen-1-boronsaeure (54354-55-1)

Guidance literature:

With sodium periodate; ammonium acetate; In water; acetone; at 20 ℃; for 24h;

DOI:10.1016/j.chempr.2021.10.015

Reference yield:

1-iodo-1-hexyne (1119-67-1) → (Z)-1-Hexen-1-boronsaeure (54354-55-1)

Guidance literature:

Multi-step reaction with 2 steps

1: azodicarboxylic acid , AcOH / methanol

2: (i) nBuLi, (ii) (nBuO)3B, (iii) aq. NaOH

With potassium diazodicarboxylate; acetic acid; In methanol;

DOI:10.1021/jo00896a020

upstream raw materials:

(Z)-1-iodohex-1-ene

1-iodo-1-hexyne

hex-1-yne

benzo[1,3,2]dioxaborole

Refernces

• 1、 Kabalka, George W.,Gooch, E. Eugene,Hsu, Henry C.. "A CONVENIENT PROCEDURE FOR THE SYNTHESES OF VINYL IODIDES VIA THE REACTION OF IODINE MONOCHLORIDE WITH VINYLBORONIC ACIDS". . p. 247 - 252. Retrieved 2007/10/02.