Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI)

Base Information

• Chemical Name: Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI)
• CAS No.: 54582-23-9
• Molecular Formula: C9H11NO
• Molecular Weight: 149.192
• Mol file: 54582-23-9.mol

Synonyms:Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI)

Chemical Property of Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI)

Chemical Property:

• PSA: 32.59000
• LogP: 2.19320

Purity/Quality:

(E)-1-(p-Tolyl)ethanoneoxime 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI)

There total 5 articles about Ethanone, 1-(4-methylphenyl)-, oxime, (1E)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

para-methylacetophenone (122-00-9) → 1-p-tolylethanone oxime (54582-23-9)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In methanol; Heating;

DOI:10.1021/jo070297k

Reference yield: 99.0%

→ 1-p-tolylethanone oxime (54582-23-9)

Guidance literature:

With ethyl acetohydroximate; scandium tris(trifluoromethanesulfonate); In ethanol; at 40 ℃; for 24h; stereoselective reaction; Inert atmosphere;

Reference yield: 90.0%

1-(p-tolyl)ethylamine (42070-98-4) → 1-p-tolylethanone oxime (54582-23-9)

Guidance literature:

With Candida antarctica Lipase type B; urea hydrogen peroxide adduct; ethyl acetate; at 30 ℃; for 1h; under 760.051 Torr; Enzymatic reaction;

DOI:10.1039/c7ob00374a

upstream raw materials:

para-methylacetophenone

1-ethenyl-4-methylbenzene

4-n-methylphenylacetylene

1-(p-tolyl)ethylamine

Downstream raw materials:

2-(4-tolyl)pyrrole

1,2-bis(p-methylphenylethylideneaminooxy)ethane

4-Methylacetanilide

para-methylacetophenone

Refernces

• 1、 Dai, Hui-Xiong,Guo, Zi-Qiong,Ma, Biao,Wang, Xing,Wang, Zhen-Yu,Xu, Hui. "C3-Arylation of indoles with aryl ketonesviaC-C/C-H activations". supporting information. p. 9716 - 9719. Retrieved 2021/09/30.
• 2、 Han, Ziwei,Lv, Jianguang,Zhang, Jianmin. "One-pot synthesis of 2-amino-3,4-dicyanopyridines from ketoximes and tetracyanoethylene via Cu(I)-catalyzed cyclization". supporting information. p. 2162 - 2168. Retrieved 2019/02/25.