4-Benzyloxybenzophenone

Base Information

• Chemical Name: 4-Benzyloxybenzophenone
• CAS No.: 54589-41-2
• Molecular Formula: C20H16O2
• Molecular Weight: 288.346
• Hs Code.: 2914509090
• Mol file: 54589-41-2.mol

Synonyms:Methanone, phenyl[4-(phenylmethoxy)phenyl]-;

Chemical Property of 4-Benzyloxybenzophenone

Chemical Property:

• Vapor Pressure: 2.48E-08mmHg at 25°C
• Melting Point: 82-85 °C(lit.)
• Refractive Index: 1.607
• Boiling Point: 451.2 °C at 760 mmHg
• Flash Point: 199.1 °C
• PSA: 26.30000
• Density: 1.143 g/cm³
• LogP: 4.49660

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Benzyloxybenzophenone ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-Benzyloxybenzophenone

There total 16 articles about 4-Benzyloxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzyl chloride (100-44-7) + 4-Hydroxybenzophenone (1137-42-4) → (R,S)-8-{2-phenyl-2-[4-(quinol-2-ylmethoxy)phenyl]ethyl}-3,8-diaza-1-oxa-2-oxospiro[4,5]decane + (4-(benzyloxy)phenyl)(phenyl)methanone (54589-41-2)

Guidance literature:

With potassium iodide; potassium carbonate; In N-methyl-acetamide; dichloromethane;

Reference yield: 97.0%

iodobenzene (591-50-4) + chloroform (67-66-3,8013-54-5) + [4-(benzyloxy)phenyl]boronic acid (146631-00-7) → (4-(benzyloxy)phenyl)(phenyl)methanone (54589-41-2)

Guidance literature:

With potassium hydroxide; In toluene; at 60 ℃; for 8h; Solvent; Reagent/catalyst; Temperature; Time; Catalytic behavior; Sealed tube; Green chemistry;

DOI:10.1039/c9nj01786k

Reference yield: 96.0%

benzyl bromide (100-39-0) + 4-Hydroxybenzophenone (1137-42-4) → (4-(benzyloxy)phenyl)(phenyl)methanone (54589-41-2)

Guidance literature:

4-Hydroxybenzophenone; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 20h;

benzyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

upstream raw materials:

benzoyl chloride

[4-(benzyloxy)phenyl]boronic acid

benzyl chloride

4-Hydroxybenzophenone

Downstream raw materials:

1,2-bis-(4-benzyloxyphenyl)-1,2-diphenylethylene

phenyl<4-(phenylmethoxy)phenyl>methanone hydrazone

4-Hydroxybenzophenone

(R,S)-2-phenyl-2-(4-benzyloxyphenyl)acetaldehyde

Refernces

• 1、 Heidari, Bahareh,Heravi, Majid M.,Nabid, Mohammad Reza,Sedghi, Roya,Hooshmand, Seyyed Emad. "Novel palladium nanoparticles supported on β-cyclodextrin@graphene oxide as magnetically recyclable catalyst for Suzuki–Miyaura cross-coupling reaction with two different approaches in bio-based solvents". . . Retrieved 2018/11/23.
• 2、 -. "High-efficiency long-service life organic room-temperature phosphorescence material and preparation method thereof". Paragraph 0034; 0035. . Retrieved 2019/01/08.