Diisopropylzinc

Base Information

• Chemical Name: Diisopropylzinc
• CAS No.: 625-81-0
• Molecular Formula: C6H14Zn
• Molecular Weight: 151.567
• European Community (EC) Number: 693-044-0
• UNII: KRU2V5BVQ3
• Wikipedia: Diisopropylzinc
• Mol file: 625-81-0.mol

Synonyms:Diisopropylzinc;625-81-0;Diisopropylzinc(1.0Mintoluene);zinc;propane;diisopropyl zinc;Bis(isopropyl)zinc;iPr2Zn;Zinc, diisopropyl-;Bis(1-methylethyl)zinc;KRU2V5BVQ3;Zinc, bis(1-methylethyl)-;KDUNMLRPPVCIGP-UHFFFAOYSA-N;NS00122787

Chemical Property of Diisopropylzinc

Chemical Property:

• Boiling Point: 52 °C(Press: 60 Torr)
• Flash Point: 23 °F
• PSA: 0.00000
• Density: 0.895 g/mL at 25 °C
• LogP: 2.72550
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 150.038692
• Heavy Atom Count: 7
• Complexity: 6.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diisopropylzinc(1.0Mintoluene) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn,C
• Statements: 11-14/15-38-48/20-63-65-67-34-17-14
• Safety Statements: 16-36/37/39-43-62-45-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[CH-]C.C[CH-]C.[Zn+2]
• Uses: Diisopropylzinc is a general reagent used in the organic asymmetric synthesis such as the asymmetric synthesis of [6]?helicene, [5]-helicene and, enantiomerically enriched 5-pyrimidyl alkanol.

Technology Process of Diisopropylzinc

There total 2 articles about Diisopropylzinc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-iodo-propane (75-30-9) → propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + propane (74-98-6) + diisopropyl zinc (625-81-0)

Guidance literature:

With zinc; at 200 ℃; for 1h; Product distribution; Zn/Fe, 300 deg C;

Reference yield:

Zn(C3H7)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C3H7)(C9H23N3)C5H(C6H5)4 + diethylzinc (557-20-0) → Zn(C2H5)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C2H5)(C9H23N3)C5H(C6H5)4 + diisopropyl zinc (625-81-0)

Guidance literature:

In benzene-d6; stirred for a few min, left standing in NMR tube at 22°C for 1 h; reversible reaction; not isolated; (1)H NMR spectral data; Kinetics;

DOI:10.1021/om000427e

Reference yield: 96.0%

diphenylzinc (1078-58-6) + diisopropyl zinc (625-81-0) → Isopropylbenzene (98-82-8)

Guidance literature:

With iron(III)-acetylacetonate; ethylene dibromide; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.200900175

upstream raw materials:

2-iodo-propane

diethylzinc

Downstream raw materials:

(E)-1-methoxy-4-(3-methyl-but-1-en-1-yl)benzene

N-2.6-Dimethylaminoisopropylaldimin

[2-Methyl-prop-(E)-ylidene]-p-tolyl-amine

[2-Methyl-prop-(E)-ylidene]-o-tolyl-amine

Refernces

• 1、 Pochekutova, T. S.,Khamylov, V. K.,Domrachev, G. A.,Zhuk, B. V.. "DIRECT SYNTHESIS OF DIPROPYL- AND DIISOPROPYLZINC". . p. 1904 - 1908. Retrieved 2007/10/02.