1-IODO-4-METHYLPENTANE

Base Information

• Chemical Name: 1-IODO-4-METHYLPENTANE
• CAS No.: 6196-80-1
• Molecular Formula: C6H13I
• Molecular Weight: 212.074
• Mol file: 6196-80-1.mol

Synonyms:1-IODO-4-METHYLPENTANE;4-METHYL-1-IODOPENTANE

Chemical Property of 1-IODO-4-METHYLPENTANE

Chemical Property:

• Melting Point: -68.15°C (estimate)
• Refractive Index: 1.4867
• Boiling Point: 174.5°C (estimate)
• PSA: 0.00000
• Density: 1.4217
• LogP: 2.85760

Purity/Quality:

97% ^*data from raw suppliers

1-IODO-4-METHYLPENTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-IODO-4-METHYLPENTANE

There total 5 articles about 1-IODO-4-METHYLPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-Methyl-1-pentanol (626-89-1) → 1-iodo-4-methylpentane (6196-80-1)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In diethyl ether; acetonitrile; at 0 - 20 ℃; Inert atmosphere;

DOI:10.3762/bjoc.8.14

Reference yield: 55.0%

1-bromo-5-methylpentane (626-88-0) → 1-iodo-4-methylpentane (6196-80-1)

Guidance literature:

With potassium iodide; In acetone; for 0.5h; Heating;

DOI:10.1016/S0040-4020(97)00837-5

Reference yield: 45.0%

4-methylpentyl 4-methylbenzenesulfonate → 1-iodo-4-methylpentane (6196-80-1)

Guidance literature:

With sodium iodide; In acetone; for 24h; Ambient temperature;

DOI:10.1021/ja00184a035

upstream raw materials:

4-Methyl-1-pentanol

1-bromo-5-methylpentane

hydrogen iodide

4-Methylpentanoic acid

Downstream raw materials:

2,2,6-Trimethyl-heptanoic acid methyl ester

2-methyloctadecan-8-one

(2S-cis)-7,8-epoxy-2-methyloctadecane

2-methyl-5-(phenylsulfonyl)pentan-2-ol

Refernces

• 1、 Du, Shaofu,Kimball, Elizabeth Ann,Ragains, Justin R.. "Visible-Light-Promoted Remote C-H Functionalization of o-Diazoniaphenyl Alkyl Sulfones". supporting information. p. 5553 - 5556. Retrieved 2017/10/25.
• 2、 Ornstein, Paul L.,Bleisch, Thomas J.,Arnold, M. Brian,Wright, Rebecca A.,Johnson, Bryan G.,Schoepp, Darryle D.. "2-substituted-(2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1- yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 1. Effects of alkyl, arylalkyl, and diarylalkyl substitution". . p. 346 - 357. Retrieved 2007/10/03.