Ser-Ala

Base Information

• Chemical Name: Ser-Ala
• CAS No.: 6403-17-4
• Molecular Formula: C₆H₁₂N₂O₄
• Molecular Weight: 176.172
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID20426566
• Nikkaji Number: J151.133E
• Wikidata: Q27144912
• Metabolomics Workbench ID: 78956
• ChEMBL ID: CHEMBL192867
• Mol file: 6403-17-4.mol

Synonyms:seryl-alanine;serylalanine

Chemical Property of Ser-Ala

Chemical Property:

• PSA: 112.65000
• LogP: -1.01350
• Storage Temp.: -15°C
• XLogP3: -3.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 176.07970687
• Heavy Atom Count: 12
• Complexity: 182

Purity/Quality:

99% ^*data from raw suppliers

Ser-Ala-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)O)NC(=O)C(CO)N
• Isomeric SMILES: C[C@@H](C(=O)O)NC(=O)[C@H](CO)N

Technology Process of Ser-Ala

There total 4 articles about Ser-Ala which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cbz-L-ser-L-ala-Cbz (6402-95-5) → L-ser-L-ala (6403-17-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 24h; under 4654.33 Torr;

DOI:10.1039/b509920j DOI:10.1039/b515880j

Reference yield:

C16H21NO7 → L-ser-L-ala (6403-17-4)

Guidance literature:

C₁₆H₂₁NO₇; (S)-Ala ester salt; With 4-methyl-morpholine; In dichloromethane; at -15 - 20 ℃;

With hydrogen; palladium on activated charcoal; In methanol; for 24h; under 4654.46 Torr; Further stages.;

DOI:10.1002/chem.200501639

Reference yield:

methyl ((benzyloxy)carbonyl)-L-seryl-L-alaninate (38428-20-5) → L-ser-L-ala (6403-17-4)

Guidance literature:

Multistep reaction; (i) aq. NaOH, MeOH, (ii) H₂, Pd-C, MeOH, H₂O;

DOI:10.1246/bcsj.41.974

upstream raw materials:

N-Benzyloxycarbonyl-L-seryl-L-alanin

methyl ((benzyloxy)carbonyl)-L-seryl-L-alaninate

Cbz-L-ser-L-ala-Cbz

Refernces

• 1、 Cordova, Armando,Zou, Weibiao,Dziedzic, Pawel,Ibrahem, Ismail,Reyes, Efraim,Xu, Yongmei. "Direct asymmetric intermolecular aldol reactions catalyzed by amino acids and small peptides". . p. 5383 - 5397. Retrieved 2008/02/13.