5,6-DIHYDROXYFLAVONE

Base Information

• Chemical Name: 5,6-DIHYDROXYFLAVONE
• CAS No.: 6665-66-3
• Molecular Formula: C15H10O4
• Molecular Weight: 254.242
• Hs Code.: 2914400090
• Mol file: 6665-66-3.mol

Synonyms:5,6-dihydroxy-2-phenyl-chromen-4-one;5,6-Dihydroxy-2-phenyl-chromen-4-on;5,6-DIHYDROXYFLAVONE;5,6-Dihydroxyflavon;

Chemical Property of 5,6-DIHYDROXYFLAVONE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 189-190 °C
• Refractive Index: 1.699
• Boiling Point: 494.399°C at 760 mmHg
• PKA: 6.55±0.40(Predicted)
• Flash Point: 193.53°C
• PSA: 70.67000
• Density: 1.443g/cm³
• LogP: 2.87120

Purity/Quality:

98%Min ^*data from raw suppliers

5,6-DIHYDROXYFLAVONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-DIHYDROXYFLAVONE

There total 30 articles about 5,6-DIHYDROXYFLAVONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

6-hydroxyflavone (6665-83-4) → 5,6-Dihydroxyflavone (6665-66-3)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 25 ℃; for 1h;

DOI:10.1016/j.tet.2010.06.014

Reference yield: 96.0%

5-Hydroxyflavone (491-78-1,66585-06-6) → 5,6-Dihydroxyflavone (6665-66-3)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 25 ℃; for 1h; regioselective reaction;

DOI:10.3390/molecules24142553

Reference yield: 6.0%

5-Hydroxyflavone (491-78-1,66585-06-6) → primetin (548-58-3) + 5,6-Dihydroxyflavone (6665-66-3)

Guidance literature:

With sodium hydroxide; potassium peroxomonosulphate; In water; at 15 - 20 ℃; for 28h;

DOI:10.1271/bbb.68.369

upstream raw materials:

primetin

6-hydroxy-5-methoxy-2-phenyl-4H-chromen-4-one

8-hydroxy-5-methoxy-2-phenyl-chromen-4-one

5,8-dimethoxy-2-phenyl-chromen-4-one

Downstream raw materials:

5,6-diacetoxy-2-phenyl-chromen-4-one

5-hydroxy-6-methoxy-2-phenyl-4H-chromen-4-one

5,6-dimethoxyflavone

6-hydroxy-5-methoxy-2-phenyl-4H-chromen-4-one

Refernces

• 1、 -. "2-substituted benzopyran-4-one compounds and application thereof". Paragraph 0161; 0162; 0163. . Retrieved 2016/10/08.
• 2、 -. "COMPOUNDS FOR IMMUNOPOTENTIATION". Page/Page column 119. . Retrieved 2010/02/15.