1-Piperazinecarbonyl chloride (9CI)

Base Information

• Chemical Name: 1-Piperazinecarbonyl chloride (9CI)
• CAS No.: 69433-07-4
• Molecular Formula: C5H9ClN2O
• Molecular Weight: 148.59076
• Mol file: 69433-07-4.mol

Synonyms:1-Piperazinecarbonyl chloride (9CI)

Chemical Property of 1-Piperazinecarbonyl chloride (9CI)

Chemical Property:

• PSA: 32.34000
• LogP: 0.51710

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Piperazinecarbonyl chloride (9CI)

There total 1 articles about 1-Piperazinecarbonyl chloride (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.9%

piperazine (110-85-0) + bis(trichloromethyl) carbonate (32315-10-9) → piperazinecarbonyl chloride (69433-07-4)

Guidance literature:

With Sodium hydrogenocarbonate; In dichloromethane; at 0 - 5 ℃;

DOI:10.1016/j.jics.2021.100165

Reference yield:

piperazinecarbonyl chloride (69433-07-4) + 7,8-dihydroxyflavone (38183-03-8) → 4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(piperazine-1-carboxylate) dihydrochloride

Guidance literature:

With dmap; In dichloromethane; at 20 ℃;

upstream raw materials:

piperazine

bis(trichloromethyl) carbonate

Refernces

• 1、 Bansal, Yogita,Kaur, Sukhvir. "Dual inhibitors of Interleukin-6 and acetylcholinesterase for treatment of Alzheimer's disease: Design, docking, synthesis and biological evaluation". . . Retrieved 2021/11/13.