Pyridazine-3,6-diamine

Base Information

• Chemical Name: Pyridazine-3,6-diamine
• CAS No.: 61070-99-3
• Molecular Formula: C4H6N4
• Molecular Weight: 110.118
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID90423365
• Nikkaji Number: J90.129F
• Wikidata: Q72463050
• Mol file: 61070-99-3.mol

Synonyms:Pyridazine-3,6-diamine;61070-99-3;3,6-Diaminopyridazine;3,6-pyridazinediamine;3,6-Pyridazinediamine(9CI);MFCD05665950;SCHEMBL1255843;AMY5635;DTXSID90423365;AKOS006344508;CS-W018954;GS-3761;SB73841;AC-27292;FT-0648653;EN300-216160;J-511383

Chemical Property of Pyridazine-3,6-diamine

Chemical Property:

• Vapor Pressure: 8.73E-08mmHg at 25°C
• Melting Point: 226-228℃
• Refractive Index: 1.694
• Boiling Point: 435.5 °C at 760 mmHg
• PKA: 7.52±0.10(Predicted)
• Flash Point: 247.2 °C
• PSA: 77.82000
• Density: 1.368 g/cm³
• LogP: 0.80340
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 110.059246208
• Heavy Atom Count: 8
• Complexity: 64.4

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,6-Diaminopyridazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NN=C1N)N

Technology Process of Pyridazine-3,6-diamine

There total 1 articles about Pyridazine-3,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(4-methoxybenzyl)pyridazine-3,6-diamine → p-methoxybenzyl chloride (824-94-2) + pyridazine-3,6-diamine (61070-99-3)

Guidance literature:

With hydrogenchloride; In ethanol; for 2h; Heating;

DOI:10.1080/00397910701410830

Reference yield: 60.0%

tert-butylisonitrile (119072-55-8,7188-38-7) + 4-methoxy-benzaldehyde (123-11-5) + pyridazine-3,6-diamine (61070-99-3) → N3-(tert-butyl)-2-(4-methoxyphenyl)imidazo[1,2-b]pyridazine-3,6-diamine

Guidance literature:

4-methoxy-benzaldehyde; pyridazine-3,6-diamine; With ytterbium(III) triflate; In acetonitrile; at 20 ℃; for 0.166667h; Microwave irradiation;

tert-butylisonitrile; In acetonitrile; at 80 ℃; Reagent/catalyst; Microwave irradiation; Sealed tube;

DOI:10.1002/chem.201802877

Reference yield: 38.0%

p-methoxyphenylisonitrile (10349-38-9) + 4-chlorobenzaldehyde (104-88-1) + pyridazine-3,6-diamine (61070-99-3) → 2,7-bis(4-chlorophenyl)-N1,N8-bis(4-methoxyphenyl)diimidazo[1,2-b:2',1'-f]pyridazine-1,8-diamine

Guidance literature:

4-chlorobenzaldehyde; pyridazine-3,6-diamine; With ytterbium(III) triflate; In acetonitrile; at 20 ℃; for 0.166667h; Microwave irradiation;

p-methoxyphenylisonitrile; In acetonitrile; at 100 ℃; Microwave irradiation; Sealed tube;

DOI:10.1002/chem.201802877

Refernces