8-iso-PGF3alpha

Base Information

• Chemical Name: 8-iso-PGF3alpha
• CAS No.: 7045-31-0
• Molecular Formula: C20H32O5
• Molecular Weight: 352.47
• DSSTox Substance ID: DTXSID101318138
• Nikkaji Number: J870.279I
• Metabolomics Workbench ID: 2823
• Mol file: 7045-31-0.mol

Synonyms:8-iso-PGF3alpha;7045-31-0;(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid;9S,11R,15S-trihydroxy-5Z,13E,17Z-prostatrienoic acid-cyclo[8S,12R];8-iso Prostaglandin F3alpha;8-iso-PGF3a;9S,11R,15S-trihydroxy-5Z,13E,17Z-prostatrienoate;8-iso Prostaglandin F3 alpha;CHEBI:157746;DTXSID101318138;LMFA03110007;PD021066;SR-01000946868;SR-01000946868-1;7-[3a,5a-dihydroxy-2-(3-hydroxy-1,5-octadienyl)cyclopentyl]-5-Heptenoate;(5Z,8b,9a,11a,13E,15S,17Z)-9,11,15-trihydroxy-Prosta-5,13,17-trien-1-oate;(5Z,8b,9a,11a,13E,15S,17Z)-9,11,15-trihydroxy-Prosta-5,13,17-trien-1-oic acid;7-[3a,5a-dihydroxy-2-(3-hydroxy-1,5-octadienyl)cyclopentyl]-5-Heptenoic acid

Chemical Property of 8-iso-PGF3alpha

Chemical Property:

• Vapor Pressure: 5.43E-14mmHg at 25°C
• Refractive Index: 1.584
• Boiling Point: 541.7°C at 760 mmHg
• Flash Point: 295.4°C
• PSA: 97.99000
• Density: 1.171g/cm³
• LogP: 2.81890
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 352.22497412
• Heavy Atom Count: 25
• Complexity: 469

Purity/Quality:

99%min ^*data from raw suppliers

8-iso Prostaglandin F3α ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC=CCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
• Isomeric SMILES: CC/C=C\C[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@H]1C/C=C\CCCC(=O)O)O)O)O

Technology Process of 8-iso-PGF3alpha

There total 2 articles about 8-iso-PGF3alpha which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (Z)-7-[(1S,2S)-3,5-Dihydroxy-2-((1E,5E)-(R)-3-hydroxy-octa-1,5-dienyl)-cyclopentyl]-hept-5-enoic acid (745-64-2,3625-65-8,7045-31-0,28977-23-3,35671-28-4,35671-29-5,57793-99-4,58640-76-9)

Guidance literature:

aus (+-)-PGE(3), NaBH4;

Reference yield:

→ (Z)-7-[(1S,3S,5R)-3,5-Dihydroxy-2-((1E,5Z)-(R)-3-hydroxy-octa-1,5-dienyl)-cyclopentyl]-hept-5-enoic acid (745-64-2,3625-65-8,7045-31-0,28977-23-3,35671-28-4,35671-29-5,57793-99-4,58640-76-9)

Guidance literature:

PGE(3), NaBH4, Me.;