Phenyl trifluorovinyl ether

Base Information

• Chemical Name: Phenyl trifluorovinyl ether
• CAS No.: 772-53-2
• Molecular Formula: C8H5F3O
• Molecular Weight: 174.122
• Hs Code.: 2909309090
• European Community (EC) Number: 641-290-4
• DSSTox Substance ID: DTXSID90579078
• Nikkaji Number: J953.704J
• Mol file: 772-53-2.mol

Synonyms:Phenyl trifluorovinyl ether;772-53-2;1,2,2-trifluoroethenoxybenzene;[(trifluoroethenyl)oxy]benzene;SCHEMBL2330129;DTXSID90579078;HVUFSELLSNXJCA-UHFFFAOYSA-N;AKOS005063681

Chemical Property of Phenyl trifluorovinyl ether

Chemical Property:

• Vapor Pressure: 14.6mmHg at 25°C
• Refractive Index: 1.454
• Boiling Point: 125.7°C at 760 mmHg
• Flash Point: 35.5°C
• PSA: 9.23000
• Density: 1.248g/cm³
• LogP: 3.10050
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 174.02924926
• Heavy Atom Count: 12
• Complexity: 169

Purity/Quality:

99% ^*data from raw suppliers

PhenylTrifluorovinylEther ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC(=C(F)F)F

Technology Process of Phenyl trifluorovinyl ether

There total 16 articles about Phenyl trifluorovinyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-phenoxytetrafluoropropionic acid (1252017-26-7) → (1,2,2-trifluorovinyloxy)benzene (772-53-2)

Guidance literature:

2-phenoxytetrafluoropropionic acid; With potassium hydroxide; In methanol; Inert atmosphere;

at 250 - 280 ℃; Inert atmosphere;

DOI:10.1021/ol500766v

Reference yield: 76.0%

1,2-dibromo-1,1,2-trifluoroethane (354-04-1) + phenol (108-95-2,27073-41-2) → (1,2,2-trifluorovinyloxy)benzene (772-53-2)

Guidance literature:

phenol; With potassium hydroxide; In water; dimethyl sulfoxide; at 100 ℃; for 6h;

1,2-dibromo-1,1,2-trifluoroethane; In water; dimethyl sulfoxide; at 60 ℃; Reagent/catalyst; Solvent; Temperature; Time;

Reference yield: 76.0%

C9H5F4O3(1-)*K(1+) (206667-03-0) → (1,2,2-trifluorovinyloxy)benzene (772-53-2)

Guidance literature:

at 240 - 260 ℃; Inert atmosphere; Pyrolysis;

DOI:10.1021/ol500766v

upstream raw materials:

1,1,2,2-tetrafluoro-1-bromo-2-phenoxyethane

phenol

2-phenoxytetrafluoropropionic acid

potassium phenolate

Downstream raw materials:

C₁₆H₁₀F₆O₂

C₈H₅ClF₈OS

2-bromo-1-(4-((trifluorovinyl)oxy)phenyl)propan-1-one

Refernces

• 1、 Ohashi, Masato,Adachi, Takuya,Ishida, Naoyoshi,Kikushima, Kotaro,Ogoshi, Sensuke. "Synthesis and Reactivity of Fluoroalkyl Copper Complexes by the Oxycupration of Tetrafluoroethylene". . p. 11911 - 11915. Retrieved 2017/09/21.
• 2、 Vaidyanathaswamy,Raman, G. Anantha,Ramkumar,Anand, Rajdeep. "Nucleophilic difluoroalkylation of benzophenones, benzaldehydes and Schiff's bases by tetrafluoroethyl ether and difluoroacetamide". . p. 38 - 49. Retrieved 2015/03/05.