2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER

Base Information

• Chemical Name: 2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER
• CAS No.: 608534-41-4
• Molecular Formula: C20H24BNO2
• Molecular Weight: 321.22
• Hs Code.: 2933990090
• Mol file: 608534-41-4.mol

Synonyms:2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER;2-(9H-Carbazolyl)ethylboronic acid pinacol cyclic ester

Chemical Property of 2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER

Chemical Property:

• Vapor Pressure: 1.87E-06mmHg at 25°C
• Melting Point: 111-113°C
• Refractive Index: 1.563
• Boiling Point: 395.2°C at 760 mmHg
• Flash Point: 192.8°C
• PSA: 23.39000
• Density: 1.08g/cm³
• LogP: 4.88670

Purity/Quality:

98%Min ^*data from raw suppliers

2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER

There total 7 articles about 2-(9H-CARBAZOLYL)ETHYLBORONIC ACID PINACOL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

9-vinyl-9H-carbazole (1484-13-5,25067-59-8) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 9-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)-9H-carbazole (608534-41-4)

Guidance literature:

With (bis(diisopropylphenyl-imidazol-2-ylidene)phenyl)CoN₂; In benzene; at 20 ℃; for 3h; chemoselective reaction;

DOI:10.1021/acscatal.7b00362

Reference yield: 74.0%

9-vinyl-9H-carbazole (1484-13-5,25067-59-8) + 2,3-dimethyl-2,3-butane diol (76-09-5) → 9-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)-9H-carbazole (608534-41-4)

Guidance literature:

Multistep reaction;

DOI:10.1002/anie.200351312

Reference yield:

9-vinyl-9H-carbazole (1484-13-5,25067-59-8) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → N-ethylcarbazole (86-28-2) + C12H8NCH2CH(B(O2C2(CH3)4))2 (1190639-26-9) + C20H22BNO2 (1190639-24-7) + 9-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)-9H-carbazole (608534-41-4)

Guidance literature:

With Wilkinson's catalyst; In tetrahydrofuran; for 18h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2009.05.016

upstream raw materials:

9-vinyl-9H-carbazole

2,3-dimethyl-2,3-butane diol

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

Downstream raw materials:

2-carbazol-9-yl-ethanol

Refernces

• 1、 Pecak, Jan,Fleissner, Sarah,Veiros, Luis F.,Pittenauer, Ernst,St?ger, Berthold,Kirchner, Karl. "Synthesis and Catalytic Reactivity of Cobalt Pincer Nitrosyl Hydride Complexes". . p. 278 - 285. Retrieved 2021/02/03.
• 2、 Xie, Qiqiang,Dong, Guangbin. "Aza-Matteson Reactions via Controlled Mono-and Double-Methylene Insertions into Nitrogen-Boron Bonds". supporting information. p. 14422 - 14427. Retrieved 2021/09/29.