9-FLUORENONE-4-CARBONYL CHLORIDE

Base Information

• Chemical Name: 9-FLUORENONE-4-CARBONYL CHLORIDE
• CAS No.: 7071-83-2
• Molecular Formula: C14H7ClO2
• Molecular Weight: 242.661
• Hs Code.: 2918300090
• Mol file: 7071-83-2.mol

Synonyms:9-OXO-4-FLUORENECARBONYL CHLORIDE;9-FLUORENONE-4-CARBONYL CHLORIDE;TIMTEC-BB SBB000824

Chemical Property of 9-FLUORENONE-4-CARBONYL CHLORIDE

Chemical Property:

• Vapor Pressure: 2.89E-07mmHg at 25°C
• Melting Point: 139-141 °C(lit.)
• Refractive Index: 1.672
• Boiling Point: 420.1°C at 760 mmHg
• Flash Point: 177.4°C
• PSA: 34.14000
• Density: 1.417g/cm³
• LogP: 3.27700
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

9-Fluorenone-4-carbonyl chloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34-40
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 9-Fluorenone-4-carbonyl chloride was used to functionalize amino acids in alkaline medium before their enantioresolution by HPLC. It was also used in the synthesis of N-(2-hydroxyethyl)-9-oxo-9H-fluorene-4 carboxamide.

Technology Process of 9-FLUORENONE-4-CARBONYL CHLORIDE

There total 6 articles about 9-FLUORENONE-4-CARBONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-oxo-9H-fluorene-4-carboxylic acid (6223-83-2) → 9-fluorenone-4-carbonyl chloride (7071-83-2)

Guidance literature:

With phosphorus pentachloride;

Reference yield:

2,4-di-tert-amylphenol (120-95-6) + 9-oxo-9H-fluorene-4-carboxylic acid (6223-83-2) → 9-fluorenone-4-carbonyl chloride (7071-83-2)

Guidance literature:

With thionyl chloride; triethylamine; In hexane; toluene;

Reference yield:

diphenic acid (863305-32-2) → 9-fluorenone-4-carbonyl chloride (7071-83-2)

Guidance literature:

With trichlorophosphate;

upstream raw materials:

diphenic acid

9-oxo-9H-fluorene-4-carboxylic acid

biphenyl-2,2'-dicarboxylic acid anhydride

benzene

Downstream raw materials:

9,9-bis-phenylsulfanyl-fluorene-4-carbothioic acid S-phenyl ester

9-oxo-9H-fluorene-4-carboxylic acid

4-cyano-9-fluorenone

C₄₉H₆₀N₄O₂₂

Refernces

• 1、 Hwu, Jih Ru,Huang, Joseph Jen Tse,Tsai, Fu-Yuan,Tsay, Shwu-Chen,Hsu, Ming-Hua,Hwang, Kuo Chu,Horng, Jia-Cherng,Ho, Ja An Annie,Lin, Chun-Cheng. "Photochemical activities of n-nitroso carboxamides and sulfoximides and their application to DNA cleavage". experimental part. p. 8742 - 8750. Retrieved 2010/03/31.
• 2、 Annunziata, Rita,Molteni, Valentina,Raimondi, Laura. "Synthesis and structural assignment of 2,4′-disubstituted benzylidenefluorenes and 4′-substituted benzylidene-1-azafluorenes". . p. 520 - 528. Retrieved 2007/10/03.