(S)-4-NONANOLIDE STANDARD FOR GC

Base Information

• Chemical Name: (S)-4-NONANOLIDE STANDARD FOR GC
• CAS No.: 63357-97-1
• Molecular Formula: C9H16O2
• Molecular Weight: 156.22214
• Mol file: 63357-97-1.mol

Synonyms:(S)-4-NONANOLIDE STANDARD FOR GC;(s)-γ-pentyl-γ-butyrolactone;(S)-γ-Pentyl-γ-butyrolactone, (S)-Dihydro-5-pentyl-2(3H)-furanone

Chemical Property of (S)-4-NONANOLIDE STANDARD FOR GC

Chemical Property:

• PSA: 26.30000
• LogP: 2.27230
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

(S)-4-NONANOLIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of (S)-4-NONANOLIDE STANDARD FOR GC

There total 54 articles about (S)-4-NONANOLIDE STANDARD FOR GC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S)-4-Hydroxy-nonanoic acid benzylamide → (S)-γ-nonanolide (63357-97-1,57084-16-9)

Guidance literature:

(S)-4-Hydroxy-nonanoic acid benzylamide; With methanol; sodium hydroxide; for 3h; Reflux;

With hydrogenchloride; In water; at 20 ℃; for 1h;

DOI:10.1080/00397910903134618

Reference yield: 97.0%

(S)-2-[(S)-4-hydroxynonanamide]-3-phenyl-N-[(R)-1-phenylethyl]propanamide (1219498-08-4) → (S)-γ-nonanolide (63357-97-1,57084-16-9) + (S)-2-amino-3-phenyl-N-[(R)-1-phenylethyl]propanamide (133287-30-6)

Guidance literature:

With hydrogenchloride; In methanol; for 3h; Reflux;

DOI:10.3987/COM-09-11863

Reference yield: 81.0%

4-hydroxy-nonanoic acid benzylamide (259675-57-5) → (S)-γ-nonanolide (63357-97-1,57084-16-9)

Guidance literature:

4-hydroxy-nonanoic acid benzylamide; With vinyl acetate; Novozym 435; In diethyl ether; at 20 ℃; Enzymatic reaction;

With di-isopropyl azodicarboxylate; triphenylphosphine; 4-nitro-benzoic acid; In benzene; at 20 ℃; for 48h; optical yield given as %ee; Further stages;

DOI:10.1080/00397910802546177

upstream raw materials:

(S)-4-Hydroxy-nonanoic acid

4-oxononanenitrile

C₁₉H₃₃⁽²⁾HO₃

C₁₉H₃₂⁽²⁾H₂O₃

Refernces

• 1、 Costa, Nuno,Matos, Sara,Da Silva, Marco D. R. Gomes,Pereira, M. Manuela A.. "Cyclodextrin-based ionic liquids as enantioselective stationary phases in gas chromatography". . p. 1466 - 1474. Retrieved 2014/01/06.
• 2、 Shimotori, Yasutaka,Miyakoshi, Tetsuo. "Combination of novozym 435-catalyzed hydrolysis and mitsunobu reaction for production of (r)γ-lactones". experimental part. p. 1607 - 1613. Retrieved 2010/06/21.