5-Amino-1-methylindoline 97%

Base Information

• Chemical Name: 5-Amino-1-methylindoline 97%
• CAS No.: 64180-07-0
• Molecular Formula: C₉H₁₂N₂
• Molecular Weight: 148.208
• Hs Code.: 2933990090
• Mol file: 64180-07-0.mol

Synonyms:Indoline,5-amino-1-methyl- (6CI); (1-Methylindolin-5-yl)amine; 1-Methyl-5-aminoindoline;5-Amino-N-methylindoline

Chemical Property of 5-Amino-1-methylindoline 97%

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 37.5-38.5°C
• Refractive Index: 1.62
• Boiling Point: 331.95°C at 760 mmHg
• PKA: 7.76±0.20(Predicted)
• Flash Point: 129.242°C
• PSA: 29.26000
• Density: 1.124g/cm³
• LogP: 1.90730

Purity/Quality:

98%min ^*data from raw suppliers

1-Methyl-2,3-dihydro-1H-indol-5-ylamine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Amino-1-methylindoline 97%

There total 6 articles about 5-Amino-1-methylindoline 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1-Methyl-5-nitroindoline (18711-25-6) → 1-methylindolin-5-amine (64180-07-0)

Guidance literature:

With tin(ll) chloride; In ethyl acetate; at 20 ℃;

Reference yield:

tin(II)chloride dihydrate + 1-Methyl-5-nitroindoline (18711-25-6) → 1-methylindolin-5-amine (64180-07-0)

Guidance literature:

With hydrogenchloride; In diethyl ether;

Reference yield:

5-nitro-2,3-dihydro-1H-indole (32692-19-6) → 1-methylindolin-5-amine (64180-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / acetone / 0 - 20 °C

2: tin(ll) chloride / ethyl acetate / 20 °C

With potassium hydroxide; tin(ll) chloride; In ethyl acetate; acetone;

upstream raw materials:

4-(1-methyl-indolin-5-ylazo)-benzenesulfonic acid

N-methylindoline

1-Methyl-5-nitroindoline

5-nitro-2,3-dihydro-1H-indole

Downstream raw materials:

N-(1-methyl-indol-5-yl)-benzamide

1-methyl-1H-indol-5-amine

5-bromo-1-methyl-H-indole

Refernces

• 1、 -. "ANTIFUNGAL AGENTS". Page/Page column 50-51. . Retrieved 2008/06/13.
• 2、 -. "Amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing same". Page/Page column 55. . Retrieved 2008/06/13.