4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID

Base Information

• Chemical Name: 4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID
• CAS No.: 70961-08-9
• Molecular Formula: C₅H₈F₃NO₂
• Molecular Weight: 171.119
• Hs Code.: 2922499990
• Mol file: 70961-08-9.mol

Synonyms:4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID

Chemical Property of 4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID

Chemical Property:

• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.402
• Boiling Point: 259°C at 760 mmHg
• Flash Point: 110.4°C
• PSA: 63.32000
• Density: 1.356g/cm³
• LogP: 1.44110

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-5,5,5-trifluoropentanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID

There total 3 articles about 4-AMINO-5,5,5-TRIFLUOROPENTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

methyl 5,5,5-trifluoro-4-(phenylamino)pentanoate (914613-28-8) → 4-amino-5,5,5-trifluoropentanoic acid (70961-08-9)

Guidance literature:

methyl 5,5,5-trifluoro-4-(phenylamino)pentanoate; With ammonium cerium (IV) nitrate; In water; acetonitrile; for 2h;

With hydrogenchloride; In water; acetonitrile; for 1h;

DOI:10.1002/ejoc.200901424

Reference yield:

→ 4-amino-5,5,5-trifluoropentanoic acid (70961-08-9)

Guidance literature:

Reference yield:

→ 4-amino-5,5,5-trifluoropentanoic acid (70961-08-9) + 4-amino-4-trifluoromethylpentanoic acid

Guidance literature:

upstream raw materials:

methyl 5,5,5-trifluoro-4-(phenylamino)pentanoate

Refernces

• 1、 -. "Halomethyl derivatives of gamma-aminobutyric acid and related compounds". . . Retrieved 2008/06/13.