P-ISOPROPYL-PHENYL-P-TOLYL-AMINE

Base Information

• Chemical Name: P-ISOPROPYL-PHENYL-P-TOLYL-AMINE
• CAS No.: 494834-22-9
• Molecular Formula: C16H19N
• Molecular Weight: 225.334
• Hs Code.: 2921440000
• Mol file: 494834-22-9.mol

Synonyms:4-Methyl-4'-isopropyldiphenylamine;

Chemical Property of P-ISOPROPYL-PHENYL-P-TOLYL-AMINE

Chemical Property:

• Vapor Pressure: 5.52E-05mmHg at 25°C
• Refractive Index: 1.587
• Boiling Point: 347.1 °C at 760 mmHg
• Flash Point: 169.4 °C
• PSA: 12.03000
• Density: 1.015 g/cm³
• LogP: 4.93500
• Storage Temp.: 2-8°C

Purity/Quality:

99.3% ^*data from raw suppliers

4-Isopropyl-N-p-tolylaniline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-ISOPROPYL-PHENYL-P-TOLYL-AMINE

There total 4 articles about P-ISOPROPYL-PHENYL-P-TOLYL-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

→ 4-isopropyl-N-(para-tolyl)aniline (494834-22-9)

Guidance literature:

With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; for 24h; Reflux;

Reference yield:

C17H21NO → 4-isopropyl-N-(para-tolyl)aniline (494834-22-9)

Guidance literature:

With trifluoroacetic acid; zinc; In methanol; at 25 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1021/ol4007162

Reference yield:

4-methyl-N-(4-methylphenyl)benzenesulfonamide (599-86-0) → 4-isopropyl-N-(para-tolyl)aniline (494834-22-9)

Guidance literature:

Multi-step reaction with 3 steps

1: [bis(acetoxy)iodo]benzene / 0.08 h / 25 °C / Schlenk technique; Inert atmosphere

2: bismuth(lll) trifluoromethanesulfonate / methanol / 25 °C / Schlenk technique; Inert atmosphere

3: zinc; trifluoroacetic acid / methanol / 25 °C / Schlenk technique; Inert atmosphere

With bismuth(lll) trifluoromethanesulfonate; [bis(acetoxy)iodo]benzene; trifluoroacetic acid; zinc; In methanol;

DOI:10.1021/ol4007162

upstream raw materials:

4-methyl-N-(4-methylphenyl)benzenesulfonamide

N-(4-methoxy-4-methylcyclohexa-2,5-dien-1-ylidene)-4-methylbenzenesulfonamide

Refernces

• 1、 Zhang, Li,Wang, Weibin,Fan, Renhua. "One-pot synthesis of diarylamines from two aromatic amines via oxidative dearomatization-imino exchange-reductive aromatization". . p. 2018 - 2021. Retrieved 2013/05/23.