6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin

Base Information

• Chemical Name: 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin
• CAS No.: 39052-32-9
• Molecular Formula: C₁₇H₁₈N₂O₂
• Molecular Weight: 282.342
• Mol file: 39052-32-9.mol

Synonyms:

Chemical Property of 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin

There total 7 articles about 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2-(2-Aminoethyl)-4,5-dimethoxybenzophenonoxim → 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin (39052-32-9)

Guidance literature:

With phosphorus pentachloride; In toluene; for 5h; cooling;

Reference yield:

N'-phenyl-N-<2-(3,4-dimethoxyphenyl)ethyl>urea (67616-08-4) → 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin (39052-32-9)

Guidance literature:

With toluene; trichlorophosphate;

DOI:10.1039/jr9340001263

Reference yield:

3,4-dimethoxyphenethyl isocyanate (35167-81-8) → 6,7-Dimethoxy-1-[(E)-phenylimino]-1,2,3,4-tetrahydroisochinolin (39052-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene

2: phosphoryl chloride; toluene

With toluene; trichlorophosphate;

DOI:10.1039/jr9340001263

upstream raw materials:

N'-phenyl-N-<2-(3,4-dimethoxyphenyl)ethyl>urea

3,4-dimethoxyphenethyl isocyanate

methyl 3-(3,4-dimethoxyphenyl)propionate

3-(3,4-dimethoxy-phenyl)-propionyl azide

Refernces