2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide

Base Information

• Chemical Name: 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide
• CAS No.: 1190105-66-8
• Molecular Formula: Br*C₃₄H₅₅N₂O₄
• Molecular Weight: 635.726
• Mol file: 1190105-66-8.mol

Synonyms:

Chemical Property of 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide

Chemical Property:

• Melting Point: >144oC (dec.)
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Pyrrolidinyl-3-acetylDesmorpholinylrocuroniumBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide is an impuritiy of Rocuronium bromide (R639500), an aminosteroid and a competitive neuromuscular blocker. 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide (Rocuronium EP Impurity F) is an impuritiy of Rocuronium bromide (R639500), an aminosteroid and a competitive neuromuscular blocker.

Technology Process of 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide

There total 1 articles about 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3-hydroxy-17-acetoxyandrostane (119302-24-8) → Br(1-)*C34H55N2O4(1+) (1190105-66-8) + rocuronium bromide

Guidance literature:

allyl bromide; With sodium carbonate; In acetone; at 20 ℃; for 0.5h;

(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3-hydroxy-17-acetoxyandrostane; In acetone; at 40 ℃; for 22h; Product distribution / selectivity;

upstream raw materials:

(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3-hydroxy-17-acetoxyandrostane

Refernces