alpha-D-glucopyranosyl 6-O-phosphono-alpha-D-glucopyranoside

Base Information

• Chemical Name: alpha-D-glucopyranosyl 6-O-phosphono-alpha-D-glucopyranoside
• CAS No.: 14752-85-3
• Molecular Formula: C₁₂H₂₃O₁₄P
• Molecular Weight: 422.28
• Mol file: 14752-85-3.mol

Synonyms:

Chemical Property of alpha-D-glucopyranosyl 6-O-phosphono-alpha-D-glucopyranoside

Chemical Property:

• Vapor Pressure: 7.99E-29mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of alpha-D-glucopyranosyl 6-O-phosphono-alpha-D-glucopyranoside

There total 19 articles about alpha-D-glucopyranosyl 6-O-phosphono-alpha-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-O-diphenoxyphosphoryl-α,α-D-trehalose (1253891-13-2) → trehalose-6-phosphate (4484-88-2,14752-85-3)

Guidance literature:

With platinum(IV) oxide; hydrogen; acetic acid; In ethanol; water; at 20 ℃; for 14h;

DOI:10.1039/c0ob00226g

Reference yield: 87.0%

6-O-(dimethoxyphosphoryl)-D-trehalose (1274878-36-2) → trehalose-6-phosphate (4484-88-2,14752-85-3)

Guidance literature:

With trimethylsilyl iodide; In 1,4-dioxane; at 20 ℃; for 0.25h;

DOI:10.1021/ol303271z

Reference yield: 52.0%

6-O-(dimethoxyphosphoryl)-D-trehalose (1274878-36-2) → 6-azido-trehalose (1274877-19-8) + trehalose-6-phosphate (4484-88-2,14752-85-3)

Guidance literature:

6-O-(dimethoxyphosphoryl)-D-trehalose; With trimethylsilyl bromide; In 1,4-dioxane; at 20 ℃; for 3h;

With water; In 1,4-dioxane;

upstream raw materials:

D-Fructose

D-glucose

D-Glucose

2,3,4,2',3',4′,6'-heptakis-O-(trimethylsilyl)-α,α-trehalose

Refernces

• 1、 Miaoa, Yi,Tenorb, Jennifer L.,Toffalettib, Dena L.,Washingtona, Erica J.,Liuc, Jiuyu,Shadrickc, William R.,Schumachera, Maria A.,Leec, Richard E.,Perfectb, John R.,Brennana, Richard G.. "Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis". . p. 7148 - 7153. Retrieved 2016.
• 2、 -. "MODIFICATION OF TREHALOSE-6-PHOSPHATE LEVELS IN PLANTS". . . Retrieved 2012/11/13.