2-Ethoxy-benzenesulfonyl chloride

Base Information

• Chemical Name: 2-Ethoxy-benzenesulfonyl chloride
• CAS No.: 68800-33-9
• Molecular Formula: C8H9 Cl O3 S
• Molecular Weight: 220.677
• Hs Code.: 2909309090
• Mol file: 68800-33-9.mol

Synonyms:2-Ethoxybenzenesulfonylchloride

Chemical Property of 2-Ethoxy-benzenesulfonyl chloride

Chemical Property:

• Melting Point: 60-64℃
• PSA: 51.75000
• LogP: 3.09360
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive

Purity/Quality:

98%Min ^*data from raw suppliers

2-EthoxybenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Ethoxybenzenesulfonyl chloride is used as pharmaceutical intermediates.

Technology Process of 2-Ethoxy-benzenesulfonyl chloride

There total 2 articles about 2-Ethoxy-benzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

Phenetole (103-73-1) → 2-ethoxybenzene-1-sulfonyl chloride (68800-33-9)

Guidance literature:

Phenetole; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; at 0 ℃; for 1h;

With sulfur dioxide; In diethyl ether; at -78 - 20 ℃; for 1.5h;

With thionyl chloride; In diethyl ether; at 20 ℃; for 6h;

Reference yield:

→ 2-ethoxybenzene-1-sulfonyl chloride (68800-33-9)

Guidance literature:

Phenetol-o-sulfinsaeure, Cl2;

Reference yield: 60.0%

2-ethoxybenzene-1-sulfonyl chloride (68800-33-9) + 2-carbomethoxyaniline (134-20-3) → methyl 2-(2-ethoxyphenylsulfonamido)benzoate

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

upstream raw materials:

Phenetole

Refernces