2,3-Difluoro-4'-pentyl-1,1'-biphenyl

Base Information

• Chemical Name: 2,3-Difluoro-4'-pentyl-1,1'-biphenyl
• CAS No.: 121219-17-8
• Molecular Formula: C₁₇H₁₈F₂
• Molecular Weight: 260.327
• DSSTox Substance ID: DTXSID40442182
• Wikidata: Q72463614
• Mol file: 121219-17-8.mol

Synonyms:121219-17-8;2,3-Difluoro-4'-pentyl-1,1'-biphenyl;2,3-DIFLUORO-4'-PENTYLBIPHENYL;1,2-difluoro-3-(4-pentylphenyl)benzene;2,3-Difluoro-4/'-pentyl-1,1/'-biphenyl;SCHEMBL7786808;DTXSID40442182;PANPSUSDKWILEG-UHFFFAOYSA-N;2',3'-difluoro-4-pentylbiphenyl;4'-n-pentyl-2,3-difluorobiphenyl;AKOS015917653;SB66296;3-(4-pentylphenyl)-1,2-difluorobenzene;FT-0687697

Chemical Property of 2,3-Difluoro-4'-pentyl-1,1'-biphenyl

Chemical Property:

• Boiling Point: 334.358 °C at 760 mmHg
• Flash Point: 130.838 °C
• PSA: 0.00000
• Density: 1.06 g/cm³
• LogP: 5.36450
• XLogP3: 6.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 260.13765690
• Heavy Atom Count: 19
• Complexity: 246

Purity/Quality:

98% or more ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC1=CC=C(C=C1)C2=C(C(=CC=C2)F)F

Technology Process of 2,3-Difluoro-4'-pentyl-1,1'-biphenyl

There total 8 articles about 2,3-Difluoro-4'-pentyl-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.8%

1-bromo-2,3-difluorobenzene (38573-88-5) + (4-pentylphenyl)boronic acid (121219-12-3) → 2,3-difluoro-4'-pentylbiphenyl (121219-17-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In N,N-dimethyl acetamide; at 100 ℃; for 8h; Inert atmosphere;

Reference yield: 53.0%

4-iodine-pentyl benzene (85017-60-3) + (2,3-difluorophenyl)boronic acid (121219-16-7) → 2,3-difluoro-4'-pentylbiphenyl (121219-17-8)

Guidance literature:

With palladium diacetate; potassium carbonate; In water; acetone; at 40 ℃; for 72h; Inert atmosphere; Reflux;

Reference yield:

4-pentylbromobenzene (51554-95-1) + (2,3-difluorophenyl)boronic acid (121219-16-7) → 2,3-difluoro-4'-pentylbiphenyl (121219-17-8)

Guidance literature:

4-pentylbromobenzene; (2,3-difluorophenyl)boronic acid; With potassium carbonate; In water; acetone; for 0.333333h; Inert atmosphere; Reflux;

With palladium diacetate; In water; acetone; for 6h; Inert atmosphere; Reflux;

DOI:10.1039/c3tc31461h

upstream raw materials:

ortho-difluorobenzene

4-pentylbromobenzene

bromobenzene

4'-bromovalerophenone

Refernces

• 1、 -. "POLYMERIZABLE COMPOUND AND OPTICAL ANISOTROPIC BODY". Paragraph 0127-0128. . Retrieved 2016/10/08.
• 2、 -. "Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy". . . Retrieved 2013/03/26.