HYDRIDE-L

Base Information Edit

Chemical Name:HYDRIDE-L
CAS No.:41639-74-1
Molecular Formula:C18H22O4
Molecular Weight:302.37
Hs Code.:2918199090
Mol file:41639-74-1.mol

Synonyms:2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(3-hydroxy-5-phenyl-1-pentenyl)-, [3aR-[3aa,4a(1E,3S*),5b,6aa]]-;2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]-,(3aR,4R,5R,6aS)- (9CI);PGX 9;

Suppliers and Price of HYDRIDE-L

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(3aR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one 95+%
250mg
$ 309.00

Crysdot
(3aR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one 95+%
1g
$ 772.00

Chemenu
(3aR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one 95%
1g
$ 729.00

AvaChem
Hydride-L for latanoprost
50mg
$ 490.00

American Custom Chemicals Corporation
(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-5-PHENYL-1-PENTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE 95.00%
5MG
$ 502.17

Alichem
(3aR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one
1g
$ 640.56

Total 67 raw suppliers

Chemical Property of HYDRIDE-L Edit

Chemical Property:

Refractive Index:1.64
Boiling Point:509.18 °C at 760 mmHg
Flash Point:185.604 °C
PSA：66.76000
Density:1.287 g/cm³
LogP:1.84880
Storage Temp.:2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(3aR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses PGX 9 is a useful intermediate in the chemoenzymatic synthesis of Latanoprost and Bimatoprost, that are prostaglandin analogs widely used for glaucoma treatment.

Technology Process of HYDRIDE-L

There total 34 articles about HYDRIDE-L which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 933789-26-5
(3aR,4R,5R,6aS)-5-hydroxy-4-((E)-3-oxo-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one

: 41639-74-1
(3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-5-phenyl-3-hydroxy-(1E)-pentenyl]-2H-cyclopentane [β] furan-2-one

Guidance literature:: (3aR,4R,5R,6aS)-5-hydroxy-4-((E)-3-oxo-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one; With chlorobis(2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl)borane; In tetrahydrofuran; at -40 ℃; for 12h;

With hydrogenchloride; In water; at 20 ℃; for 0.5h; Reagent/catalyst; Temperature;