Thiol-PEG8-acid

Base Information

• Chemical Name: Thiol-PEG8-acid
• CAS No.: 866889-02-3
• Molecular Formula: C19H38 O10 S
• Molecular Weight: 458.56400
• DSSTox Substance ID: DTXSID50584840
• Nikkaji Number: J2.728.188E
• Wikidata: Q72488610
• Mol file: 866889-02-3.mol

Synonyms:Thiol-PEG8-acid;866889-02-3;HS-PEG8-CH2CH2COOH;1-mercapto-3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid;SH-PEG8-COOH;O-(2-Carboxyethyl)-O'-(2-mercaptoethyl)heptaethylene glycol;1-mercapto-3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oicacid;Thiol-PEG8-propionic acid;1-SULFANYL-3,6,9,12,15,18,21,24-OCTAOXAHEPTACOSAN-27-OIC ACID;4,7,10,13,16,19,22,25-Octaoxaheptacosanoicacid, 27-mercapto-;SCHEMBL40095;DTXSID50584840;27-Mercapto-4,7,10,13,16,19,22,25-Octaoxaheptacosanoicacid;3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-mercapto-;MFCD08274610;AKOS028113963;AS-70980;BP-21915;HY-130542;CS-0109045;C70178;3-[2-[2-[2-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Chemical Property of Thiol-PEG8-acid

Chemical Property:

• Boiling Point: 559.7±50.0 °C(Predicted)
• PKA: 4.28±0.10(Predicted)
• PSA: 149.94000
• Density: 1.141±0.06 g/cm3(Predicted)
• LogP: 0.52370
• Storage Temp.: ?20°C
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 26
• Exact Mass: 458.21856858
• Heavy Atom Count: 30
• Complexity: 349

Purity/Quality:

98%,99%, ^*data from raw suppliers

O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol ≥95% (oligomer purity) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCS)C(=O)O
• Description: Thiol-PEG8-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
• Uses: O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol can be used:To prepare near-infrared fluorochromes applicable in imaging techniques.To functionalize Au nanoparticles for optoelectronic applications.As a linker in the synthesis of antibody-functionalized Au nanoparticles for forensic applications.