4-(2-Thienyl)benzenesulfonyl chloride

Base Information

• Chemical Name: 4-(2-Thienyl)benzenesulfonyl chloride
• CAS No.: 209592-91-6
• Molecular Formula: C10H7ClO2S2
• Molecular Weight: 258.7444
• European Community (EC) Number: 804-977-1
• DSSTox Substance ID: DTXSID20593348
• Wikidata: Q82487813
• Mol file: 209592-91-6.mol

Synonyms:209592-91-6;4-(2-thienyl)benzenesulfonyl chloride;Benzenesulfonyl chloride, 4-(2-thienyl)-;4-(Thiophen-2-yl)benzene-1-sulfonyl chloride;4-thiophen-2-ylbenzenesulfonyl chloride;F9995-0055;SCHEMBL4796613;DTXSID20593348;IRDZCMUQNGEQEP-UHFFFAOYSA-N;4-(2-thienyl)benzenesulfonylchloride;MFCD11655569;AKOS015958431;Benzenesulfonyl chloride,4-(2-thienyl)-;AS-64777;EN300-239653;G29541

Chemical Property of 4-(2-Thienyl)benzenesulfonyl chloride

Chemical Property:

• Melting Point: 107-108℃
• Boiling Point: 373.8 °C at 760 mmHg
• Flash Point: 179.8 °C
• PSA: 70.76000
• Density: 1.43 g/cm³
• LogP: 4.42340
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 257.9575995
• Heavy Atom Count: 15
• Complexity: 302

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Thienyl)benzenesulfonyl chloride 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CSC(=C1)C2=CC=C(C=C2)S(=O)(=O)Cl

Technology Process of 4-(2-Thienyl)benzenesulfonyl chloride

There total 3 articles about 4-(2-Thienyl)benzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ 4-(Thiophene-2-yl)benzenesulfonyl chloride (209592-91-6)

Guidance literature:

Reference yield:

4-(2-thienyl)benzenesulfonic acid (770692-75-6) → 4-(Thiophene-2-yl)benzenesulfonyl chloride (209592-91-6) + 4-(5-chloro-2-thienyl)benzenesulfonyl chloride (874959-67-8)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; at 50 ℃; for 3h;

Reference yield:

→ 4-(Thiophene-2-yl)benzenesulfonyl chloride (209592-91-6) + (2R)-1-[5-(4-Acetoxy-3-fluorophenyl)thiophene-2-sulfonyl]-4-methanesulfonyl-N-(2-tetrahydropyranyloxy)-2-piperazinecarboxamide (209589-86-6)

Guidance literature:

upstream raw materials:

4-(2-thienyl)benzenesulfonic acid

Refernces

• 1、 -. "Bispiperidines as antithrombotic agents". . . Retrieved 2008/06/13.