Technology Process of C19H28ClN3O4S*C2HF3O2
There total 12 articles about C19H28ClN3O4S*C2HF3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: potassium carbonate / 1,4-dioxane; water / 3 h / 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 5 h / 0 - 20 °C
3: piperidine / dichloromethane / 1 h / 20 °C
4: triethylamine / dichloromethane / 16 h / 0 - 20 °C
5: triethylamine / dichloromethane / 1 h / -10 - 20 °C
6: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 20 °C
7: potassium carbonate / methanol / 0.5 h / 20 °C
8: dichloromethane / 2 h / 20 °C
With
piperidine; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.01.002
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 1 h / -10 - 20 °C
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 20 °C
3: potassium carbonate / methanol / 0.5 h / 20 °C
4: dichloromethane / 2 h / 20 °C
With
potassium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane;
DOI:10.1016/j.bmcl.2014.01.002
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 5 h / 0 - 20 °C
2: piperidine / dichloromethane / 1 h / 20 °C
3: triethylamine / dichloromethane / 16 h / 0 - 20 °C
4: triethylamine / dichloromethane / 1 h / -10 - 20 °C
5: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.5 h / 20 °C
6: potassium carbonate / methanol / 0.5 h / 20 °C
7: dichloromethane / 2 h / 20 °C
With
piperidine; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.01.002