4-Hydroxy-4-methyl-2-oxoglutarate

Base Information

• Chemical Name: 4-Hydroxy-4-methyl-2-oxoglutarate
• CAS No.: 64215-73-2
• Molecular Formula: C₆H₆O₆
• Molecular Weight: 174.11
• DSSTox Substance ID: DTXSID301215350
• Wikidata: Q27125663
• Mol file: 64215-73-2.mol

Synonyms:4-Hydroxy-4-methyl-2-oxoglutarate;2-hydroxy-2-methyl-4-oxopentanedioate;4-hydroxy-4-methyl-2-oxoglutarate(2-);64215-73-2;CHEBI:58276;DTXSID301215350;4-hydroxy-4-carboxy-2-oxovalerate;4-hydroxy-4-methyl-2-ketoglutarate;4-hydroxy-4-methyl-2-oxoglutarate dianion;Q27125663;Pentanedioic acid, 2-hydroxy-2-methyl-4-oxo-, ion(2-)

Chemical Property of 4-Hydroxy-4-methyl-2-oxoglutarate

Chemical Property:

• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 174.01643791
• Heavy Atom Count: 12
• Complexity: 221

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CC(=O)C(=O)[O-])(C(=O)[O-])O

Technology Process of 4-Hydroxy-4-methyl-2-oxoglutarate

There total 1 articles about 4-Hydroxy-4-methyl-2-oxoglutarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piruvate (57-60-3) + phosphoenolpyruvic acid (73-89-2,67533-04-4) → 4-methyl-4-hydroxy-2-oxoglutarate (64215-73-2)

Guidance literature:

With white potato acid phosphatase; magnesium(II); at 25 ℃; Rate constant; Equilibrium constant; acetate/ acetic acid buffer, using instead of Mg⁽²⁺⁾, Zn⁽²⁺⁾;

DOI:10.1021/ja00189a028

upstream raw materials:

piruvate

phosphoenolpyruvic acid

Refernces