4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt

Base Information

• Chemical Name: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt
• CAS No.: 474710-80-0
• Molecular Formula: C9H8BrN3O2
• Molecular Weight: 270.08
• Hs Code.: 2933990090
• Mol file: 474710-80-0.mol

Synonyms:Ammonium 6-bromoquinazoline-4-carboxylate;4-Quinazolinecarboxylic acid,6-bromo-,ammonium salt;

Chemical Property of 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.722
• Boiling Point: 497.1 °C at 760 mmHg
• Flash Point: 254.4 °C
• PSA: 66.32000
• Density: 1.824g/cm³
• LogP: 2.41440
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Ammonium6-bromoquinazoline-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt

There total 1 articles about 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-N-formylisatin (474710-79-7) → ammonium 6-bromoquinazoline-4-carboxylate (474710-80-0)

Guidance literature:

5-bromo-N-formylisatin; With sodium hydroxide; In water; at 30 ℃; for 0.166667h;

With hydrogenchloride; In water; at 0 ℃;

With ammonia; In ethanol; at 100 ℃; for 2.5h;

Reference yield:

methanol (67-56-1) + ammonium 6-bromoquinazoline-4-carboxylate (474710-80-0) → methyl 6-bromoquinazolin-4-carboxylate (474710-78-6)

Guidance literature:

With sulfuric acid; for 4h; Heating / reflux;

upstream raw materials:

5-bromo-N-formylisatin

Downstream raw materials:

methyl 6-bromoquinazolin-4-carboxylate

Refernces