1-Methylpiperidin-4-amine hydrochloride

Base Information

• Chemical Name: 1-Methylpiperidin-4-amine hydrochloride
• CAS No.: 1193-03-9
• Molecular Formula: C₆H₁₄N₂*2ClH
• Molecular Weight: 187.112
• Hs Code.: 2933399090
• Mol file: 1193-03-9.mol

Synonyms:1-methylpiperidin-4-amine hydrochloride;120088-53-1;1193-03-9;1-methylpiperidin-4-amine HCl;4-Amino-1-methylpiperidine hydrochloride;1-methylpiperidin-4-amine;hydrochloride;4-Piperidinamine, 1-methyl-, hydrochloride (1:1);4-amino-1-methylpiperidine dihydrochloride;DXMYKAREPXBRHQ-UHFFFAOYSA-N;BAA19303;MFCD20526326;1-methylpiperidin-4-aminehydrochloride;AKOS027257232;SB41192;BS-14540;SY022054;DB-097983;CS-0151104;D82382;1-methylpiperidin-4-amine hydrogen chloride salt

Chemical Property of 1-Methylpiperidin-4-amine hydrochloride

Chemical Property:

• Melting Point: 101-110 °C (lit.)
• Boiling Point: 267.8 °C at 760 mmHg
• Flash Point: 115.8 °C
• PSA: 29.26000
• Density: 1.24 g/cm³
• LogP: 1.47950
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 150.0923762
• Heavy Atom Count: 9
• Complexity: 64.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Fluorobenzene boronic acid ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCC(CC1)N.Cl

Technology Process of 1-Methylpiperidin-4-amine hydrochloride

There total 1 articles about 1-Methylpiperidin-4-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Amino-1-methylpiperidine (41838-46-4) → 4-amino-1-methylpiperidine dihydrochloride (1193-03-9,120088-53-1)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 20 ℃; for 1h;

Reference yield: 28.0%

4-amino-1-methylpiperidine dihydrochloride (1193-03-9,120088-53-1) + benzoyl chloride (98-88-4) → N-(1-methyl-4-piperidinyl)benzamide hydrochloride

Guidance literature:

benzoyl chloride; With 1H-imidazole; In acetonitrile; at 20 ℃;

4-amino-1-methylpiperidine dihydrochloride; With 1H-imidazole; In acetonitrile; at 20 ℃;

DOI:10.3987/COM-18-S(F)97

Reference yield:

4-amino-1-methylpiperidine dihydrochloride (1193-03-9,120088-53-1) + benzoyl chloride (98-88-4) → N-(1-methyl-4-piperidinyl)benzamide hydrochloride

Guidance literature:

With 1H-imidazole; In acetonitrile; at 15 - 30 ℃;

upstream raw materials:

4-Amino-1-methylpiperidine

Refernces